Abstract
1. Morphine added to hashed brain tissue of the rat decreases the oxygen consumption due to added glucose.
2. Brain from non-tolerant animals killed one hour after a subcutaneous injection of morphine show an increased oxygen consumption over the normal for a period of four to five hours, due to the increased glucose.
3. Brain from morphine-tolerant rats exhibits the same metabolic rate as that from normal animals.
4. Subcutaneous injection of morphine into non-tolerant animals produces no change in the metabolic rate of kidney and testis.
Footnotes
- Received November 16, 1934.
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