PT  - JOURNAL ARTICLE
AU  - GROSS, E. G.
AU  - PIERCE, I. H.
TI  - FFFECT OF MORPHINE ON THE OXYGEN CONSUMPTION OF BRAIN TISSUE IN THE RAT
DP  - 1935 Feb 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 156--168
VI  - 53
IP  - 2
4099  - http://jpet.aspetjournals.org/content/53/2/156.short
4100  - http://jpet.aspetjournals.org/content/53/2/156.full
SO  - J Pharmacol Exp Ther1935 Feb 01; 53
AB  - 1. Morphine added to hashed brain tissue of the rat decreases the oxygen consumption due to added glucose. 2. Brain from non-tolerant animals killed one hour after a subcutaneous injection of morphine show an increased oxygen consumption over the normal for a period of four to five hours, due to the increased glucose. 3. Brain from morphine-tolerant rats exhibits the same metabolic rate as that from normal animals. 4. Subcutaneous injection of morphine into non-tolerant animals produces no change in the metabolic rate of kidney and testis.