New multi-target antagonists of α1A-, α1D-adrenoceptors and 5-HT1A receptors reduce human hyperplastic prostate cell growth and the increase of intraurethral pressure

Jessica B Nascimento-Viana; Aline R Carvalho; Luiz Eurico Nasciutti; Rocio Alcantara-Hernandez; Fernanda Chagas-Silva; Pedro A R de Souza; Luiz A Romeiro; J Adolfo Garcia-Sainz; Francois Noel; Claudia L M Silva

doi:10.1124/jpet.115.227066

Research ArticleDrug Discovery and Translational Medicine

New multi-target antagonists of α1A-, α1D-adrenoceptors and 5-HT_1A receptors reduce human hyperplastic prostate cell growth and the increase of intraurethral pressure

Jessica B Nascimento-Viana, Aline R Carvalho, Luiz Eurico Nasciutti, Rocio Alcantara-Hernandez, Fernanda Chagas-Silva, Pedro A R de Souza, Luiz A Romeiro, J Adolfo Garcia-Sainz, Francois Noel and Claudia L M Silva

Journal of Pharmacology and Experimental Therapeutics October 22, 2015, jpet.115.227066; DOI: https://doi.org/10.1124/jpet.115.227066

Jessica B Nascimento-Viana

1 Federal University of Rio de Janeiro;

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Aline R Carvalho

1 Federal University of Rio de Janeiro;

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Luiz Eurico Nasciutti

1 Federal University of Rio de Janeiro;

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Rocio Alcantara-Hernandez

2 Universidad Nacional Autonoma de Mexico;

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Fernanda Chagas-Silva

1 Federal University of Rio de Janeiro;

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Pedro A R de Souza

1 Federal University of Rio de Janeiro;

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Luiz A Romeiro

3 Brasilia University;

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J Adolfo Garcia-Sainz

4 Univerdidad Nacional Autonoma de Mexico

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Francois Noel

1 Federal University of Rio de Janeiro;

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Claudia L M Silva

1 Federal University of Rio de Janeiro;

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Journal of Pharmacology and Experimental Therapeutics

Vol. 391, Issue 3

1 Dec 2024

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Research ArticleDrug Discovery and Translational Medicine

New multi-target antagonists of α1A-, α1D-adrenoceptors and 5-HT_1A receptors reduce human hyperplastic prostate cell growth and the increase of intraurethral pressure

Journal of Pharmacology and Experimental Therapeutics October 22, 2015, jpet.115.227066; DOI: https://doi.org/10.1124/jpet.115.227066

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Research ArticleDrug Discovery and Translational Medicine

New multi-target antagonists of α1A-, α1D-adrenoceptors and 5-HT_1A receptors reduce human hyperplastic prostate cell growth and the increase of intraurethral pressure

Journal of Pharmacology and Experimental Therapeutics October 22, 2015, jpet.115.227066; DOI: https://doi.org/10.1124/jpet.115.227066

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New multi-target antagonists of α1A-, α1D-adrenoceptors and 5-HT_1A receptors reduce human hyperplastic prostate cell growth and the increase of intraurethral pressure

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New multi-target antagonists of α1A-, α1D-adrenoceptors and 5-HT_1A receptors reduce human hyperplastic prostate cell growth and the increase of intraurethral pressure

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