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Research ArticleDrug Discovery and Translational Medicine

Differential Impact of Amino Acid Substitutions on Critical Residues of the Human Glucagon-Like Peptide-1 Receptor (GLP-1R) Involved in Peptide Activity and Small Molecule Allostery

Cassandra Koole, Denise Wootten, John Simms, Laurence J Miller, Arthur Christopoulos and Patrick M Sexton
Journal of Pharmacology and Experimental Therapeutics January 28, 2015, jpet.114.220913; DOI: https://doi.org/10.1124/jpet.114.220913
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Research ArticleDrug Discovery and Translational Medicine

Differential Impact of Amino Acid Substitutions on Critical Residues of the Human Glucagon-Like Peptide-1 Receptor (GLP-1R) Involved in Peptide Activity and Small Molecule Allostery

Cassandra Koole, Denise Wootten, John Simms, Laurence J Miller, Arthur Christopoulos and Patrick M Sexton
Journal of Pharmacology and Experimental Therapeutics January 28, 2015, jpet.114.220913; DOI: https://doi.org/10.1124/jpet.114.220913
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