Research ArticleDrug Discovery and Translational Medicine
NS19504: A Novel BK Channel Activator with Relaxing Effect on Bladder Smooth Muscle Spontaneous Phasic Contractions
Bernhard Nausch, Frederik Rode, Susanne Jørgensen, Antonio Nardi, Mads P. G. Korsgaard, Charlotte Hougaard, Adrian D. Bonev, William D. Brown, Tino Dyhring, Dorte Strøbæk, Søren-Peter Olesen, Palle Christophersen, Morten Grunnet, Mark T. Nelson and Lars C. B. Rønn
Journal of Pharmacology and Experimental Therapeutics September 2014, 350 (3) 520-530; DOI: https://doi.org/10.1124/jpet.113.212662
Bernhard Nausch
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Frederik Rode
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Susanne Jørgensen
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Antonio Nardi
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Mads P. G. Korsgaard
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Charlotte Hougaard
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Adrian D. Bonev
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
William D. Brown
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Tino Dyhring
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Dorte Strøbæk
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Søren-Peter Olesen
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Palle Christophersen
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Morten Grunnet
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Mark T. Nelson
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
Lars C. B. Rønn
NeuroSearch A/S, Ballerup, Denmark (F.R., S.J., A.N., M.P.G.K., C.H., W.D.B., T.D., D.S., S.-P.O., P.C., M.G., L.C.B.R.); University of Vermont, Department of Pharmacology, Burlington, Vermont (B.N., A.D.B., M.T.N.); and Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom (M.T.N.)
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Research ArticleDrug Discovery and Translational Medicine
NS19504 Inhibits Bladder Strip Contractions
Bernhard Nausch, Frederik Rode, Susanne Jørgensen, Antonio Nardi, Mads P. G. Korsgaard, Charlotte Hougaard, Adrian D. Bonev, William D. Brown, Tino Dyhring, Dorte Strøbæk, Søren-Peter Olesen, Palle Christophersen, Morten Grunnet, Mark T. Nelson and Lars C. B. Rønn
Journal of Pharmacology and Experimental Therapeutics September 1, 2014, 350 (3) 520-530; DOI: https://doi.org/10.1124/jpet.113.212662
Research ArticleDrug Discovery and Translational Medicine
NS19504 Inhibits Bladder Strip Contractions
Bernhard Nausch, Frederik Rode, Susanne Jørgensen, Antonio Nardi, Mads P. G. Korsgaard, Charlotte Hougaard, Adrian D. Bonev, William D. Brown, Tino Dyhring, Dorte Strøbæk, Søren-Peter Olesen, Palle Christophersen, Morten Grunnet, Mark T. Nelson and Lars C. B. Rønn
Journal of Pharmacology and Experimental Therapeutics September 1, 2014, 350 (3) 520-530; DOI: https://doi.org/10.1124/jpet.113.212662
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