Abstract
The frequency of writhing motions in mice given phenylquinone intraperitoneally can be altered by low doses of Na acetylsalicylate and other low potency analgesic agents.
Antagonism of the frequency of writhing is afforded by a variety of agents not usually classified as analgesics.
The sensitivity of the test is greater when based on the number of writhing motions rather than on the all-or-none response.
Footnotes
- Received September 19, 1958.
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