RT Journal Article
SR Electronic
T1 ANTAGONISM OF THE FREQUENCY OF PHENYLQUINONE-INDUCED WRITHING IN THE MOUSE BY WEAK ANALGESICS AND NONANALGESICS
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 237
OP 240
VO 125
IS 3
A1 Hendershot, L. C.
A1 Forsaith, Janet
YR 1959
UL http://jpet.aspetjournals.org/content/125/3/237.abstract
AB The frequency of writhing motions in mice given phenylquinone intraperitoneally can be altered by low doses of Na acetylsalicylate and other low potency analgesic agents. Antagonism of the frequency of writhing is afforded by a variety of agents not usually classified as analgesics. The sensitivity of the test is greater when based on the number of writhing motions rather than on the all-or-none response.