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Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates
Steven M. Weldon, Matthew A. Cerny, Kristina Gueneva-Boucheva, Derek Cogan, Xin Guo, Neil Moss, Jean-Hugues Parmentier, Jeremy R. Richman, Glenn A. Reinhart and Nicholas F. Brown

Journal of Pharmacology and Experimental Therapeutics October 2016, 359 (1) 142-150; DOI: https://doi.org/10.1124/jpet.116.236463
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Significant Improvement of Antithrombotic Responses to Clopidogrel by Use of a Novel Conjugate as Revealed in an Arterial Model of Thrombosis
Haoming Zhang, D. Adam Lauver, Hui Wang, Duxin Sun, Paul F. Hollenberg, Y. Eugene Chen, Yoichi Osawa and Daniel T. Eitzman

Journal of Pharmacology and Experimental Therapeutics October 2016, 359 (1) 11-17; DOI: https://doi.org/10.1124/jpet.116.236034
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Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
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Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556
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Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
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Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146
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Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
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Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors
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Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 423-430; DOI: https://doi.org/10.1124/jpet.116.232322
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Treatment with Adenosine Receptor Agonist Ameliorates Pain Induced by Acute and Chronic Inflammation
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Cerebrospinal Fluid Calbindin D Concentration as a Biomarker of Cerebellar Disease Progression in Niemann-Pick Type C1 Disease
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Prostaglandin E₂-Glyceryl Ester: In Vivo Evidence for a Distinct Pharmacological Identity from Intraocular Pressure Studies
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Journal of Pharmacology and Experimental Therapeutics August 2016, 358 (2) 173-180; DOI: https://doi.org/10.1124/jpet.116.232512
Open Access
The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif

Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256

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