Abstract
The curve of blood alcohol plotted against time, after a single dose of from 0.5 to 1.5 cc. per kilogram administered intravenously to man, is a straight line, the rate of decline being independent of the height of the blood alcohol, but varying considerably from individual to individual.
The amount of alcohol per unit time required to maintain the blood alcohol of an individual at a given concentration is constant and independent of the height of the blood alcohol, at least within the limits of this investigation, 15 to 94 mgm. per 100 cc. The average for our subjects was 0.174 cc. per kilogram per hour, closely approximating the value of 0.185 cc. obtained by Mellanby in dogs.
Footnotes
- Received April 15, 1935.
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