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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

8-Aminoguanosine Exerts Diuretic, Natriuretic, and Glucosuric Activity via Conversion to 8-Aminoguanine, Yet Has Direct Antikaliuretic Effects

Edwin K. Jackson and Zaichuan Mi
Journal of Pharmacology and Experimental Therapeutics December 2017, 363 (3) 358-366; DOI: https://doi.org/10.1124/jpet.117.243758

Article Information

vol. 363 no. 3 358-366
DOI 
https://doi.org/10.1124/jpet.117.243758
PubMed 
28928119
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 1, 2017
  • Accepted September 18, 2017
  • Published online November 8, 2017.

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Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Edwin K. Jackson and
  2. Zaichuan Mi
  1. Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
  1. Address correspondence to:
    Dr. Edwin K. Jackson, Department of Pharmacology and Chemical Biology, 100 Technology Drive, Room 514, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219. E-mail: edj{at}pitt.edu
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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

8-Aminoguanosine Is a Prodrug

Edwin K. Jackson and Zaichuan Mi
Journal of Pharmacology and Experimental Therapeutics December 1, 2017, 363 (3) 358-366; DOI: https://doi.org/10.1124/jpet.117.243758
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