Research ArticleDrug Discovery and Translational Medicine
Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates
Steven M. Weldon, Matthew A. Cerny, Kristina Gueneva-Boucheva, Derek Cogan, Xin Guo, Neil Moss, Jean-Hugues Parmentier, Jeremy R. Richman, Glenn A. Reinhart and Nicholas F. Brown
Journal of Pharmacology and Experimental Therapeutics October 2016, 359 (1) 142-150; DOI: https://doi.org/10.1124/jpet.116.236463
Steven M. Weldon
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
Matthew A. Cerny
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
Kristina Gueneva-Boucheva
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
Derek Cogan
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
Xin Guo
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
Neil Moss
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
Jean-Hugues Parmentier
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
Jeremy R. Richman
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
Glenn A. Reinhart
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
Nicholas F. Brown
CardioMetabolic Diseases Research (S.M.W., J-H. P., J.R.R., G.A.R., N.F.B.), and Medicinal Chemistry (M.A.C., K.G.B., D.C., X.G., N.M.), Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut
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Research ArticleDrug Discovery and Translational Medicine
Selectivity of BI 689648, FAD286, and LCI699 in NHPs
Steven M. Weldon, Matthew A. Cerny, Kristina Gueneva-Boucheva, Derek Cogan, Xin Guo, Neil Moss, Jean-Hugues Parmentier, Jeremy R. Richman, Glenn A. Reinhart and Nicholas F. Brown
Journal of Pharmacology and Experimental Therapeutics October 1, 2016, 359 (1) 142-150; DOI: https://doi.org/10.1124/jpet.116.236463
Research ArticleDrug Discovery and Translational Medicine
Selectivity of BI 689648, FAD286, and LCI699 in NHPs
Steven M. Weldon, Matthew A. Cerny, Kristina Gueneva-Boucheva, Derek Cogan, Xin Guo, Neil Moss, Jean-Hugues Parmentier, Jeremy R. Richman, Glenn A. Reinhart and Nicholas F. Brown
Journal of Pharmacology and Experimental Therapeutics October 1, 2016, 359 (1) 142-150; DOI: https://doi.org/10.1124/jpet.116.236463
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