Research ArticleDrug Discovery and Translational Medicine
Pegylation Improves the Pharmacokinetics and Bioavailability of Small-Molecule Drugs Hydrolyzable by Esterases: A Study of Phospho-Ibuprofen
George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208
George Mattheolabakis
Department of Medicine, Stony Brook University, Stony Brook, New York (G.M., C.C.W., Y.S., C.A.A., R.R., B.R.); and Medicon Pharmaceuticals, Inc. (P.P.C., B.R.), Stony Brook, New York
Chi C. Wong
Department of Medicine, Stony Brook University, Stony Brook, New York (G.M., C.C.W., Y.S., C.A.A., R.R., B.R.); and Medicon Pharmaceuticals, Inc. (P.P.C., B.R.), Stony Brook, New York
Yu Sun
Department of Medicine, Stony Brook University, Stony Brook, New York (G.M., C.C.W., Y.S., C.A.A., R.R., B.R.); and Medicon Pharmaceuticals, Inc. (P.P.C., B.R.), Stony Brook, New York
Carol A. Amella
Department of Medicine, Stony Brook University, Stony Brook, New York (G.M., C.C.W., Y.S., C.A.A., R.R., B.R.); and Medicon Pharmaceuticals, Inc. (P.P.C., B.R.), Stony Brook, New York
Robert Richards
Department of Medicine, Stony Brook University, Stony Brook, New York (G.M., C.C.W., Y.S., C.A.A., R.R., B.R.); and Medicon Pharmaceuticals, Inc. (P.P.C., B.R.), Stony Brook, New York
Panayiotis P. Constantinides
Department of Medicine, Stony Brook University, Stony Brook, New York (G.M., C.C.W., Y.S., C.A.A., R.R., B.R.); and Medicon Pharmaceuticals, Inc. (P.P.C., B.R.), Stony Brook, New York
Basil Rigas
Department of Medicine, Stony Brook University, Stony Brook, New York (G.M., C.C.W., Y.S., C.A.A., R.R., B.R.); and Medicon Pharmaceuticals, Inc. (P.P.C., B.R.), Stony Brook, New York
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In this issue
Research ArticleDrug Discovery and Translational Medicine
Pegylation Prevents Phospho-Ibuprofen Hydrolysis
George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
Journal of Pharmacology and Experimental Therapeutics October 1, 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208
Research ArticleDrug Discovery and Translational Medicine
Pegylation Prevents Phospho-Ibuprofen Hydrolysis
George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
Journal of Pharmacology and Experimental Therapeutics October 1, 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208
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