Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal
Astragaloside IV Ameliorates Renal Fibrosis via the Inhibition of Mitogen-Activated Protein Kinases and Antiapoptosis In Vivo and In Vitro
Weijia Xu, Xinghua Shao, Lei Tian, Leyi Gu, Minfang Zhang, Qin Wang, Bei Wu, Ling Wang, Jufang Yao, Xiaoping Xu, Shan Mou and Zhaohui Ni
Journal of Pharmacology and Experimental Therapeutics September 2014, 350 (3) 552-562; DOI: https://doi.org/10.1124/jpet.114.214205
Weijia Xu
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Xinghua Shao
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Lei Tian
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Leyi Gu
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Minfang Zhang
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Qin Wang
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Bei Wu
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Ling Wang
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Jufang Yao
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Xiaoping Xu
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Shan Mou
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Zhaohui Ni
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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In this issue
Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal
Astragaloside IV Inhibits Renal Fibrosis
Weijia Xu, Xinghua Shao, Lei Tian, Leyi Gu, Minfang Zhang, Qin Wang, Bei Wu, Ling Wang, Jufang Yao, Xiaoping Xu, Shan Mou and Zhaohui Ni
Journal of Pharmacology and Experimental Therapeutics September 1, 2014, 350 (3) 552-562; DOI: https://doi.org/10.1124/jpet.114.214205
Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal
Astragaloside IV Inhibits Renal Fibrosis
Weijia Xu, Xinghua Shao, Lei Tian, Leyi Gu, Minfang Zhang, Qin Wang, Bei Wu, Ling Wang, Jufang Yao, Xiaoping Xu, Shan Mou and Zhaohui Ni
Journal of Pharmacology and Experimental Therapeutics September 1, 2014, 350 (3) 552-562; DOI: https://doi.org/10.1124/jpet.114.214205
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