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Research ArticleNEUROPHARMACOLOGY

Pharmacokinetic-Pharmacodynamic Modeling of the Antinociceptive Effect of Buprenorphine and Fentanyl in Rats: Role of Receptor Equilibration Kinetics

Ashraf Yassen, Erik Olofsen, Albert Dahan and Meindert Danhof
Journal of Pharmacology and Experimental Therapeutics June 2005, 313 (3) 1136-1149; DOI: https://doi.org/10.1124/jpet.104.082560
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Research ArticleNEUROPHARMACOLOGY

Pharmacokinetic-Pharmacodynamic Modeling of the Antinociceptive Effect of Buprenorphine and Fentanyl in Rats: Role of Receptor Equilibration Kinetics

Ashraf Yassen, Erik Olofsen, Albert Dahan and Meindert Danhof
Journal of Pharmacology and Experimental Therapeutics June 1, 2005, 313 (3) 1136-1149; DOI: https://doi.org/10.1124/jpet.104.082560
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