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Abstract

7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization.

I Zivkovic, D M Thompson, M Bertolino, D Uzunov, M DiBella, E Costa and A Guidotti
Journal of Pharmacology and Experimental Therapeutics January 1995, 272 (1) 300-309;

Article Information

vol. 272 no. 1 300-309
PubMed 
7815345
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Published online January 1, 1995.

Author Information

  1. I Zivkovic,
  2. D M Thompson,
  3. M Bertolino,
  4. D Uzunov,
  5. M DiBella,
  6. E Costa and
  7. A Guidotti
  1. Center for Neuropharmacology, Nathan S. Kline Institute for Psychiatric Research, NYU, Orangeburg.

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    Abstract

    7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization.

    I Zivkovic, D M Thompson, M Bertolino, D Uzunov, M DiBella, E Costa and A Guidotti
    Journal of Pharmacology and Experimental Therapeutics January 1, 1995, 272 (1) 300-309;
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