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Table of Contents
January 1995; 272 (1)
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R M Arendt
,
M Schmoeckel
,
U Wilbert-Lampen
,
A Plasse
,
L Heucke
,
and
K Werdan
Bidirectional effects of endogenous opioid peptides on endothelin release rates in porcine aortic endothelial cell culture: mediation by delta opioid receptor and opioid receptor antagonist-insensitive mechanisms.
J Pharmacol Exp Ther
January 1995
272
:
1
-
7
Abstract
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A Rinken
Subtype-specific changes in ligand binding properties after solubilization of muscarinic receptors from baculovirus-infected Sf9 insect cell membranes.
J Pharmacol Exp Ther
January 1995
272
:
8
-
14
Abstract
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D Y Li
,
D R Varma
,
and
S Chemtob
Up-regulation of brain PGE2 and PGF2 alpha receptors and receptor-coupled second messengers by cyclooxygenase inhibition in newborn pigs.
J Pharmacol Exp Ther
January 1995
272
:
15
-
19
Abstract
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J J Lynch, Jr
,
J J Cook
,
G R Sitko
,
M A Holahan
,
D R Ramjit
,
M J Mellott
,
M T Stranieri
,
I I Stabilito
,
G Zhang
,
and
R J Lynch
Nonpeptide glycoprotein IIb/IIIa inhibitors. 5. Antithrombotic effects of MK-0383.
J Pharmacol Exp Ther
January 1995
272
:
20
-
32
Abstract
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S A Grevelink
,
J Osborne
,
J Loscalzo
,
and
E A Lerner
Vasorelaxant and second messenger effects of maxadilan.
J Pharmacol Exp Ther
January 1995
272
:
33
-
37
Abstract
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M A Desai
,
J P Burnett
,
P L Ornstein
,
and
D D Schoepp
Cyclothiazide acts at a site on the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists.
J Pharmacol Exp Ther
January 1995
272
:
38
-
43
Abstract
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H Parfenova
,
P Hsu
,
and
C W Leffler
Dilator prostanoid-induced cyclic AMP formation and release by cerebral microvascular smooth muscle cells: inhibition by indomethacin.
J Pharmacol Exp Ther
January 1995
272
:
44
-
52
Abstract
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J A Hewett
and
R A Roth
The coagulation system, but not circulating fibrinogen, contributes to liver injury in rats exposed to lipopolysaccharide from gram-negative bacteria.
J Pharmacol Exp Ther
January 1995
272
:
53
-
62
Abstract
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Y Tomita
,
M Takano
,
M Yasuhara
,
R Hori
,
and
K Inui
Transport of oral cephalosporins by the H+/dipeptide cotransporter and distribution of the transport activity in isolated rabbit intestinal epithelial cells.
J Pharmacol Exp Ther
January 1995
272
:
63
-
69
Abstract
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K Kushiku
,
H Ohjimi
,
H Yamada
,
T Kuwahara
,
and
T Furukawa
Activation of endogenous thromboxane A2 biosynthesis mediates presynaptic inhibition by endothelin-3 of dog stellate ganglionic transmission.
J Pharmacol Exp Ther
January 1995
272
:
70
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76
Abstract
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E Sarri
,
F Picatoste
,
and
E Claro
Neurotransmitter-specific profiles of inositol phosphates in rat brain cortex: relation to the mode of receptor activation of phosphoinositide phospholipase C.
J Pharmacol Exp Ther
January 1995
272
:
77
-
84
Abstract
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J M Kalman
,
A M Tonkin
,
and
J M Power
Specific effects of zatebradine on sinus node function: suppression of automaticity, prolongation of sinoatrial conduction and pacemaker shift in the denervated canine heart.
J Pharmacol Exp Ther
January 1995
272
:
85
-
93
Abstract
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T Aiba
,
Y Sakurai
,
S Tsukada
,
and
T Koizumi
Effects of probenecid and cimetidine on the renal excretion of 3'-azido-3'-deoxythymidine in rats.
J Pharmacol Exp Ther
January 1995
272
:
94
-
99
Abstract
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C A Sannerud
and
N A Ator
Drug discrimination analysis of midazolam under a three-lever procedure: I. Dose-dependent differences in generalization and antagonism.
J Pharmacol Exp Ther
January 1995
272
:
100
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111
Abstract
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T L Ripley
and
H J Little
Effects on ethanol withdrawal hyperexcitability of chronic treatment with a competitive N-methyl-D-aspartate receptor antagonist.
J Pharmacol Exp Ther
January 1995
272
:
112
-
118
Abstract
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J A Gibbons
,
Z P Luo
,
E R Hannon
,
R A Braeckman
,
and
J D Young
Quantitation of the renal clearance of interleukin-2 using nephrectomized and ureter-ligated rats.
J Pharmacol Exp Ther
January 1995
272
:
119
-
125
Abstract
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S M Weldon
,
R J Winquist
,
and
J B Madwed
Differential effects of L-NAME on blood pressure and heart rate responses to acetylcholine and bradykinin in cynomolgus primates.
J Pharmacol Exp Ther
January 1995
272
:
126
-
133
Abstract
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D A Schwinn
,
G I Johnston
,
S O Page
,
M J Mosley
,
K H Wilson
,
N P Worman
,
S Campbell
,
M D Fidock
,
L M Furness
,
and
D J Parry-Smith
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.
J Pharmacol Exp Ther
January 1995
272
:
134
-
142
Abstract
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D A Cox
and
M L Cohen
5-Hydroxytryptamine2B receptor signaling in rat stomach fundus: role of voltage-dependent calcium channels, intracellular calcium release and protein kinase C.
J Pharmacol Exp Ther
January 1995
272
:
143
-
150
Abstract
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J A Baron
,
R J Comi
,
V Cryns
,
T Brinck-Johnsen
,
and
N G Mercer
The effect of cigarette smoking on adrenal cortical hormones.
J Pharmacol Exp Ther
January 1995
272
:
151
-
155
Abstract
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R E Burrier
,
A A Smith
,
D G McGregor
,
L M Hoos
,
D L Zilli
,
and
H R Davis, Jr
The effect of acyl CoA: cholesterol acyltransferase inhibition on the uptake, esterification and secretion of cholesterol by the hamster small intestine.
J Pharmacol Exp Ther
January 1995
272
:
156
-
163
Abstract
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L Wang
and
D K Pitts
Ontogeny of nigrostriatal dopamine neuron autoreceptors: iontophoretic studies.
J Pharmacol Exp Ther
January 1995
272
:
164
-
176
Abstract
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T Kihara
and
M Ikeda
Effects of duloxetine, a new serotonin and norepinephrine uptake inhibitor, on extracellular monoamine levels in rat frontal cortex.
J Pharmacol Exp Ther
January 1995
272
:
177
-
183
Abstract
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Z Wang
,
B Fermini
,
and
S Nattel
Effects of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes.
J Pharmacol Exp Ther
January 1995
272
:
184
-
196
Abstract
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L A Suchar
,
R L Chang
,
R T Rosen
,
J Lech
,
and
A H Conney
High-performance liquid chromatography separation of hydroxylated estradiol metabolites: formation of estradiol metabolites by liver microsomes from male and female rats.
J Pharmacol Exp Ther
January 1995
272
:
197
-
206
Abstract
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T L Yaksh
,
J W Pogrel
,
Y W Lee
,
and
S R Chaplan
Reversal of nerve ligation-induced allodynia by spinal alpha-2 adrenoceptor agonists.
J Pharmacol Exp Ther
January 1995
272
:
207
-
214
Abstract
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J B Schachter
and
B B Wolfe
3-Isobutyl-1-methylxanthine increases alpha-1-adrenergic receptor sensitivity and density in DDT1-MF2 smooth muscle cells.
J Pharmacol Exp Ther
January 1995
272
:
215
-
223
Abstract
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J M Derocq
,
B Bourrié
,
M Ségui
,
G Le Fur
,
and
P Casellas
In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the sigma ligand SR 31747.
J Pharmacol Exp Ther
January 1995
272
:
224
-
230
Abstract
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A H Oliveto
,
M I Rosen
,
S W Woods
,
and
T R Kosten
Discriminative stimulus, self-reported and cardiovascular effects of orally administered cocaine in humans.
J Pharmacol Exp Ther
January 1995
272
:
231
-
241
Abstract
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P W Swaan
and
J J Tukker
Carrier-mediated transport mechanism of foscarnet (trisodium phosphonoformate hexahydrate) in rat intestinal tissue.
J Pharmacol Exp Ther
January 1995
272
:
242
-
247
Abstract
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L J Benincosa
,
K Sagawa
,
and
M E Morris
Renal adaptation to altered dietary sulfate in rats.
J Pharmacol Exp Ther
January 1995
272
:
248
-
255
Abstract
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M Yamazaki
,
N Matsuoka
,
N Maeda
,
K Kuratani
,
Y Ohkubo
,
and
I Yamaguchi
FR121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.
J Pharmacol Exp Ther
January 1995
272
:
256
-
263
Abstract
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D Gonzalez-Ramirez
,
R M Maiorino
,
M Zuniga-Charles
,
Z Xu
,
K M Hurlbut
,
P Junco-Munoz
,
M M Aposhian
,
R C Dart
,
J H Diaz Gama
,
and
D Echeverria
Sodium 2,3-dimercaptopropane-1-sulfonate challenge test for mercury in humans: II. Urinary mercury, porphyrins and neurobehavioral changes of dental workers in Monterrey, Mexico.
J Pharmacol Exp Ther
January 1995
272
:
264
-
274
Abstract
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S Gancher
,
J Crabbe
,
A Garland
,
E Lea
,
and
W Woodward
Dose- and duration-dependent tolerance to rotational effects of apomorphine in a rat model of Parkinsonism.
J Pharmacol Exp Ther
January 1995
272
:
275
-
281
Abstract
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O A Abdeen
,
B K Taylor
,
K L Youngblood
,
and
M P Printz
Peripheral beta adrenergic blockade modifies airpuff startle-induced heart rate responses.
J Pharmacol Exp Ther
January 1995
272
:
282
-
289
Abstract
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F L Smith
and
D L Stevens
Calcium modulation of morphine analgesia: role of calcium channels and intracellular pool calcium.
J Pharmacol Exp Ther
January 1995
272
:
290
-
299
Abstract
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I Zivkovic
,
D M Thompson
,
M Bertolino
,
D Uzunov
,
M DiBella
,
E Costa
,
and
A Guidotti
7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization.
J Pharmacol Exp Ther
January 1995
272
:
300
-
309
Abstract
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S P Welch
,
C Thomas
,
and
G S Patrick
Modulation of cannabinoid-induced antinociception after intracerebroventricular versus intrathecal administration to mice: possible mechanisms for interaction with morphine.
J Pharmacol Exp Ther
January 1995
272
:
310
-
321
Abstract
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P Y Law
and
C Bergsbaken
Properties of delta opioid receptor in neuroblastoma NS20Y: receptor activation and neuroblastoma proliferation.
J Pharmacol Exp Ther
January 1995
272
:
322
-
332
Abstract
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I Bekavac
and
B D Waterhouse
Systemically administered cocaine selectively enhances long-latency responses of rat barrel field cortical neurons to vibrissae stimulation.
J Pharmacol Exp Ther
January 1995
272
:
333
-
342
Abstract
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W Gonzalez Vera
,
M C Fournié-Zaluski
,
I Pham
,
I Laboulandine
,
B P Roques
,
and
J B Michel
Hypotensive and natriuretic effects of RB 105, a new dual inhibitor of angiotensin converting enzyme and neutral endopeptidase in hypertensive rats.
J Pharmacol Exp Ther
January 1995
272
:
343
-
351
Abstract
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V Granados-Soto
,
F J López-Muñoz
,
E Hong
,
and
F J Flores-Murrieta
Relationship between pharmacokinetics and the analgesic effect of ketorolac in the rat.
J Pharmacol Exp Ther
January 1995
272
:
352
-
356
Abstract
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K Takeuchi
,
K Takehara
,
T Kaneko
,
and
S Okabe
Nitric oxide and prostaglandins in regulation of acid secretory response in rat stomach following injury.
J Pharmacol Exp Ther
January 1995
272
:
357
-
363
Abstract
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H Movahedi
,
H T Le
,
H M Spanggord
,
and
R E Purdy
Effect of alpha adrenergic agonist on the rabbit ear artery contraction to serotonin: enhanced response mediated by serotonergic1-like receptors.
J Pharmacol Exp Ther
January 1995
272
:
364
-
370
Abstract
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Z F Gu
,
T K Pradhan
,
D H Coy
,
and
R T Jensen
Interaction of galanin fragments with galanin receptors on isolated smooth muscle cells from guinea pig stomach: identification of a novel galanin receptor subtype.
J Pharmacol Exp Ther
January 1995
272
:
371
-
378
Abstract
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M Nakashima
and
P M Vanhoutte
Isoproterenol causes hyperpolarization through opening of ATP-sensitive potassium channels in vascular smooth muscle of the canine saphenous vein.
J Pharmacol Exp Ther
January 1995
272
:
379
-
384
Abstract
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S Chakder
and
S Rattan
Distribution of VIP binding sites in opossum internal anal sphincter circular smooth muscle.
J Pharmacol Exp Ther
January 1995
272
:
385
-
391
Abstract
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S W Larkin
,
L Fraser
,
H J Showell
,
T J Williams
,
and
J B Warren
Prolonged microvascular vasodilation induced by leukotriene B4 in human skin is cyclooxygenase independent.
J Pharmacol Exp Ther
January 1995
272
:
392
-
398
Abstract
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C Stevens
,
M Lipman
,
S Fabry
,
M Moscovitch-Lopatin
,
W Almawi
,
S Keresztes
,
M A Peppercorn
,
and
T B Strom
5-Aminosalicylic acid abrogates T-cell proliferation by blocking interleukin-2 production in peripheral blood mononuclear cells.
J Pharmacol Exp Ther
January 1995
272
:
399
-
406
Abstract
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T C Jeong
,
S D Jordan
,
R A Matulka
,
E D Stanulis
,
E J Kaminski
,
and
M P Holsapple
Role of metabolism by esterase and cytochrome P-450 in cocaine-induced suppression of the antibody response.
J Pharmacol Exp Ther
January 1995
272
:
407
-
416
Abstract
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M Veljaca
,
C A Lesch
,
R Pllana
,
B Sanchez
,
K Chan
,
and
A Guglietta
BPC-15 reduces trinitrobenzene sulfonic acid-induced colonic damage in rats.
J Pharmacol Exp Ther
January 1995
272
:
417
-
422
Abstract
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K Raynor
,
H Kong
,
A Mestek
,
L S Bye
,
M Tian
,
J Liu
,
L Yu
,
and
T Reisine
Characterization of the cloned human mu opioid receptor.
J Pharmacol Exp Ther
January 1995
272
:
423
-
428
Abstract
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M P Kung
,
D Frederick
,
M Mu
,
Z P Zhuang
,
and
H F Kung
4-(2'-Methoxy-phenyl)-1-[2'-(n-2"-pyridinyl)-p-iodobenzamido]-ethyl- piperazine ([125I]p-MPPI) as a new selective radioligand of serotonin-1A sites in rat brain: in vitro binding and autoradiographic studies.
J Pharmacol Exp Ther
January 1995
272
:
429
-
437
Abstract
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I Ducić
,
H J Caruncho
,
W J Zhu
,
S Vicini
,
and
E Costa
gamma-Aminobutyric acid gating of Cl- channels in recombinant GABAA receptors.
J Pharmacol Exp Ther
January 1995
272
:
438
-
445
Abstract
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M L Cohen
,
J G Granneman
,
A Chaudhry
,
K W Schenck
,
D J Cushing
,
and
A D Palkowitz
Is the "atypical" beta-receptor in the rat stomach fundus the rat beta 3 receptor?
J Pharmacol Exp Ther
January 1995
272
:
446
-
451
Abstract
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G J Hom
,
S K Grant
,
G Wolfe
,
T J Bach
,
D E MacIntyre
,
and
N I Hutchinson
Lipopolysaccharide-induced hypotension and vascular hyporeactivity in the rat: tissue analysis of nitric oxide synthase mRNA and protein expression in the presence and absence of dexamethasone, NG-monomethyl-L-arginine or indomethacin.
J Pharmacol Exp Ther
January 1995
272
:
452
-
459
Abstract
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H M Cherwinski
,
D McCarley
,
R Schatzman
,
B Devens
,
and
J T Ransom
The immunosuppressant leflunomide inhibits lymphocyte progression through cell cycle by a novel mechanism.
J Pharmacol Exp Ther
January 1995
272
:
460
-
468
Abstract
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N Mascolo
,
A A Izzo
,
G Autore
,
F M Maiello
,
G Di Carlo
,
and
F Capasso
Acetic acid-induced colitis in normal and essential fatty acid deficient rats.
J Pharmacol Exp Ther
January 1995
272
:
469
-
475
Abstract
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