Abstract
1. Irrigations of the spinal and cerebral subarachnoid spaces are well tolerated by cats if the irrigating fluid is composed of sodium chloride, potassium chloride, and calcium chloride in proper proportions (modified Ringer's solution). If, however, the irrigation be done with isotonic solutions of sodium chloride alone, various toxic effects become apparent. Many of these animals die during or immediately after the irrigation; if this immediate toxicity is survived, convulsive seizures and acute mania are almost invariable. Recovery from such attacks is frequent.
2. Single irrigation with modified Ringer's solution of infected meningeal spaces has prolonged the life of the animals, as compared with controls. The period of survival in many cases has been doubled as a result of this washing-out of the infected meninges. Multiple irrigations have not been attempted.
Footnotes
- Received April 14, 1919.
JPET articles become freely available 12 months after publication, and remain freely available for 5 years.Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page.
|