Abstract
1. In five normotensive human subjects, the pressor effect and bradycardia of phenylephrine (Neosynephrine) administration were associated with a decreased renal blood flow.
2. This decrease in blood flow, due to increased renal resistance located chiefly in the efferent arteriole, was associated with an increased filtration fraction and a relatively unchanged glomerular filtration rate.
Footnotes
- Received October 4, 1950.
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