Antiretroviral drug concentrations in lymph nodes: a cross-species comparison of the effect of drug transporter expression, viral infection, and sex in humanized mice, nonhuman primates, and humans

Erin Burgunder; John K. Fallon; Nicole White; Amanda P Schauer; Craig Sykes; Leila Remling-Mulder; Martina Kovarova; Lourdes Adamson; Paul Luciw; J Victor Garcia; Ramesh Akkina; Philip C. Smith; Angela D.M. Kashuba

doi:10.1124/jpet.119.259150

Research ArticleMetabolism, Transport, and Pharmacogenomics

Antiretroviral drug concentrations in lymph nodes: a cross-species comparison of the effect of drug transporter expression, viral infection, and sex in humanized mice, nonhuman primates, and humans

Erin Burgunder, John K. Fallon, Nicole White, Amanda P Schauer, Craig Sykes, Leila Remling-Mulder, Martina Kovarova, Lourdes Adamson, Paul Luciw, J Victor Garcia, Ramesh Akkina, Philip C. Smith and Angela D.M. Kashuba

Journal of Pharmacology and Experimental Therapeutics June 24, 2019, jpet.119.259150; DOI: https://doi.org/10.1124/jpet.119.259150

Erin Burgunder

1 University of North Carolina at Chapel Hill;

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John K. Fallon

1 University of North Carolina at Chapel Hill;

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ORCID record for John K. Fallon

Nicole White

1 University of North Carolina at Chapel Hill;

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Amanda P Schauer

1 University of North Carolina at Chapel Hill;

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Craig Sykes

1 University of North Carolina at Chapel Hill;

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Leila Remling-Mulder

2 Colorado State University;

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Martina Kovarova

1 University of North Carolina at Chapel Hill;

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Lourdes Adamson

3 University of California at Davis

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Paul Luciw

3 University of California at Davis

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J Victor Garcia

1 University of North Carolina at Chapel Hill;

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Ramesh Akkina

2 Colorado State University;

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Philip C. Smith

1 University of North Carolina at Chapel Hill;

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Angela D.M. Kashuba

1 University of North Carolina at Chapel Hill;

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Journal of Pharmacology and Experimental Therapeutics

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Research ArticleMetabolism, Transport, and Pharmacogenomics

Antiretroviral drug concentrations in lymph nodes: a cross-species comparison of the effect of drug transporter expression, viral infection, and sex in humanized mice, nonhuman primates, and humans

Journal of Pharmacology and Experimental Therapeutics June 24, 2019, jpet.119.259150; DOI: https://doi.org/10.1124/jpet.119.259150

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Research ArticleMetabolism, Transport, and Pharmacogenomics

Antiretroviral drug concentrations in lymph nodes: a cross-species comparison of the effect of drug transporter expression, viral infection, and sex in humanized mice, nonhuman primates, and humans

Journal of Pharmacology and Experimental Therapeutics June 24, 2019, jpet.119.259150; DOI: https://doi.org/10.1124/jpet.119.259150

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Antiretroviral drug concentrations in lymph nodes: a cross-species comparison of the effect of drug transporter expression, viral infection, and sex in humanized mice, nonhuman primates, and humans

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Antiretroviral drug concentrations in lymph nodes: a cross-species comparison of the effect of drug transporter expression, viral infection, and sex in humanized mice, nonhuman primates, and humans

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