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Research ArticleDrug Discovery and Translational Medicine
Open Access

Understanding Exposure-Receptor Occupancy Relationships for Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators across a Range of Preclinical and Clinical Studies

Kirstie A. Bennett, Eugenia Sergeev, Cliona P. MacSweeney, Geor Bakker and Anne E. Cooper
Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 157-168; DOI: https://doi.org/10.1124/jpet.120.000371
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Research ArticleDrug Discovery and Translational Medicine

Exposure-Receptor Occupancy Relationships for mGlu5 NAMs

Kirstie A. Bennett, Eugenia Sergeev, Cliona P. MacSweeney, Geor Bakker and Anne E. Cooper
Journal of Pharmacology and Experimental Therapeutics April 1, 2021, 377 (1) 157-168; DOI: https://doi.org/10.1124/jpet.120.000371
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