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Research ArticleGASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438), a Novel and Potent Potassium-Competitive Acid Blocker for the Treatment of Acid-Related Diseases

Yasunobu Hori, Akio Imanishi, Jun Matsukawa, Yasuhiro Tsukimi, Haruyuki Nishida, Yasuyoshi Arikawa, Keizo Hirase, Masahiro Kajino and Nobuhiro Inatomi
Journal of Pharmacology and Experimental Therapeutics October 2010, 335 (1) 231-238; DOI: https://doi.org/10.1124/jpet.110.170274

Article Information

vol. 335 no. 1 231-238
DOI 
https://doi.org/10.1124/jpet.110.170274
PubMed 
20624992
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 16, 2010
  • Accepted July 6, 2010
  • Published online September 20, 2010.

Article Versions

Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yasunobu Hori,
  2. Akio Imanishi,
  3. Jun Matsukawa,
  4. Yasuhiro Tsukimi,
  5. Haruyuki Nishida,
  6. Yasuyoshi Arikawa,
  7. Keizo Hirase,
  8. Masahiro Kajino and
  9. Nobuhiro Inatomi
  1. Pharmaceutical Research Division (Y.H., A.I., J.M., Y.T., H.N., Y.A., K.H., N.I.) and Chemistry, Manufacturing, and Controls Center (M.K.), Takeda Pharmaceutical Company Limited, Osaka, Japan
  1. Address correspondence to:
    Dr. Nobuhiro Inatomi, Pharmacology Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 17-85, Jusohonmachi 2-chome, Yodogawa-ku, Osaka 532-8686, Japan. E-mail: inatomi_nobuhiro{at}takeda.co.jp
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Research ArticleGASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438), a Novel and Potent Potassium-Competitive Acid Blocker for the Treatment of Acid-Related Diseases

Yasunobu Hori, Akio Imanishi, Jun Matsukawa, Yasuhiro Tsukimi, Haruyuki Nishida, Yasuyoshi Arikawa, Keizo Hirase, Masahiro Kajino and Nobuhiro Inatomi
Journal of Pharmacology and Experimental Therapeutics October 1, 2010, 335 (1) 231-238; DOI: https://doi.org/10.1124/jpet.110.170274
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