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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Disposition of Flavonoids via Enteric Recycling: UDP-Glucuronosyltransferase (UGT) 1As Deficiency in Gunn Rats Is Compensated by Increases in UGT2Bs Activities

Stephen W. J. Wang, Kaustubh H. Kulkarni, Lan Tang, Jing Rong Wang, Taijun Yin, Tomo Daidoji, Hiroshi Yokota and Ming Hu
Journal of Pharmacology and Experimental Therapeutics June 2009, 329 (3) 1023-1031; DOI: https://doi.org/10.1124/jpet.108.147371

Article Information

vol. 329 no. 3 1023-1031
DOI 
https://doi.org/10.1124/jpet.108.147371
PubMed 
19264971
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received October 11, 2008
  • Accepted February 25, 2009
  • Published online May 18, 2009.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Stephen W. J. Wang,
  2. Kaustubh H. Kulkarni,
  3. Lan Tang,
  4. Jing Rong Wang,
  5. Taijun Yin,
  6. Tomo Daidoji,
  7. Hiroshi Yokota and
  8. Ming Hu
  1. Department of Pharmacological and Pharmaceutical Sciences (S.W.J.W., K.H.K., L.T., J.R.W., T.Y., M.H.) and Pharmaceutics Graduate Program (S.W.J.W., K.H.K.), College of Pharmacy, University of Houston, Houston, Texas; Department of Pharmaceutics, School of Pharmacy, Southern Medical University, Guangzhou, Guangdong, China (L.T.); School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, People's Republic of China (J.R.W.); and Department of Veterinary Biochemistry, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan (T.D., H.Y.)
  1. Address correspondence to:
    Dr. Ming Hu, Department of Pharmaceutical Sciences, College of Pharmacy, 1441 Moursund St., University of Houston, Houston, TX 77204. E-mail: mhu{at}uh.edu
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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Disposition of Flavonoids via Enteric Recycling: UDP-Glucuronosyltransferase (UGT) 1As Deficiency in Gunn Rats Is Compensated by Increases in UGT2Bs Activities

Stephen W. J. Wang, Kaustubh H. Kulkarni, Lan Tang, Jing Rong Wang, Taijun Yin, Tomo Daidoji, Hiroshi Yokota and Ming Hu
Journal of Pharmacology and Experimental Therapeutics June 1, 2009, 329 (3) 1023-1031; DOI: https://doi.org/10.1124/jpet.108.147371
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