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Research ArticleCARDIOVASCULAR

The Nitric Oxide-Donating Pravastatin Derivative, NCX 6550 [(1S-[1α(βS*, δS*), 2α, 6α, 8β-(R*), 8aα]]-1,2,6,7,8,8a-Hexahydro-β, δ, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic Acid 4-(Nitrooxy)butyl Ester)], Reduces Splenocyte Adhesion and Reactive Oxygen Species Generation in Normal and Atherosclerotic Mice

G. Dever, C. M. Spickett, S. Kennedy, C. Rush, G. Tennant, A. Monopoli and C. L. Wainwright
Journal of Pharmacology and Experimental Therapeutics January 2007, 320 (1) 419-426; DOI: https://doi.org/10.1124/jpet.106.109298

Article Information

vol. 320 no. 1 419-426
DOI 
https://doi.org/10.1124/jpet.106.109298
PubMed 
17005918
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received June 12, 2006
  • Accepted September 26, 2006
  • Published online December 20, 2006.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. G. Dever,
  2. C. M. Spickett,
  3. S. Kennedy,
  4. C. Rush,
  5. G. Tennant,
  6. A. Monopoli and
  7. C. L. Wainwright
  1. Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom (G.D., C.M.S., S.K., C.R., G.T.); Nicox Research Institute, Milan, Italy (A.M.); and School of Pharmacy, Robert Gordon University, Aberdeen, Scotland, United Kingdom (C.L.W.)
  1. Address correspondence to:
    Cherry L. Wainwright, School of Pharmacy, The Robert Gordon University, Schoolhill, Aberdeen AB10 1FR, UK. E-mail: c.wainwright{at}rgu.ac.uk
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Research ArticleCARDIOVASCULAR

The Nitric Oxide-Donating Pravastatin Derivative, NCX 6550 [(1S-[1α(βS*, δS*), 2α, 6α, 8β-(R*), 8aα]]-1,2,6,7,8,8a-Hexahydro-β, δ, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic Acid 4-(Nitrooxy)butyl Ester)], Reduces Splenocyte Adhesion and Reactive Oxygen Species Generation in Normal and Atherosclerotic Mice

G. Dever, C. M. Spickett, S. Kennedy, C. Rush, G. Tennant, A. Monopoli and C. L. Wainwright
Journal of Pharmacology and Experimental Therapeutics January 1, 2007, 320 (1) 419-426; DOI: https://doi.org/10.1124/jpet.106.109298
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