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Research ArticleNEUROPHARMACOLOGY

Protection against Cocaine Toxicity in Mice by the Dopamine D3/D2 Agonist R-(+)-trans-3,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol [(+)-PD 128,907]

J. M. Witkin, D. Dijkstra, B. Levant, H. C. Akunne, A. Zapata, S. Peters, H. E. Shannon and M. Gasior
Journal of Pharmacology and Experimental Therapeutics March 2004, 308 (3) 957-964; DOI: https://doi.org/10.1124/jpet.103.059980

Article Information

vol. 308 no. 3 957-964
DOI 
https://doi.org/10.1124/jpet.103.059980
PubMed 
14711932
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received September 12, 2003
  • Accepted November 25, 2003
  • Published online February 25, 2004.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. J. M. Witkin,
  2. D. Dijkstra,
  3. B. Levant,
  4. H. C. Akunne,
  5. A. Zapata,
  6. S. Peters,
  7. H. E. Shannon and
  8. M. Gasior1
  1. Neuroscience Discovery Research (J.M.W., S.P., H.E.S.), Lilly Research Laboratories, Eli Lilly & Co., Indianapolis, Indiana; Behavioral Neuroscience Branch (A.Z., M.G.), National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland; Department of Medicinal Chemistry (D.D.), University Centre of Pharmacy; Groningen, The Netherlands; Department of Pharmacology (B.L.), University of Kansas Medical Center; Kansas City, Kansas; and Neurosciences Pharmacology (H.C.A.), Pfizer Inc., Ann Arbor, Michigan
  1. Address correspondence to:
    Dr. J. M. Witkin, Neuroscience Discovery Research, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285-0501. E-mail: jwitkin{at}lilly.com
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Research ArticleNEUROPHARMACOLOGY

Protection against Cocaine Toxicity in Mice by the Dopamine D3/D2 Agonist R-(+)-trans-3,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol [(+)-PD 128,907]

J. M. Witkin, D. Dijkstra, B. Levant, H. C. Akunne, A. Zapata, S. Peters, H. E. Shannon and M. Gasior
Journal of Pharmacology and Experimental Therapeutics March 1, 2004, 308 (3) 957-964; DOI: https://doi.org/10.1124/jpet.103.059980
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