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Research ArticleGASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

Reduced Liver Uptake of Arterially Infused Melphalan during Retrograde Rat Liver Perfusion with Unaffected Liver Tumor Uptake

Joost Rothbarth, Rolf W. Sparidans, Jos H. Beijnen, Leo J. Schultze Kool, Hein Putter, Cornelis J. H. van de Velde and Gerard J. Mulder
Journal of Pharmacology and Experimental Therapeutics November 2002, 303 (2) 736-740; DOI: https://doi.org/10.1124/jpet.102.037895

Article Information

vol. 303 no. 2 736-740
DOI 
https://doi.org/10.1124/jpet.102.037895
PubMed 
12388659
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received April 23, 2002
  • Accepted July 22, 2002
  • Published online November 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Joost Rothbarth1,
  2. Rolf W. Sparidans4,
  3. Jos H. Beijnen4,
  4. Leo J. Schultze Kool5,
  5. Hein Putter2,
  6. Cornelis J. H. van de Velde1 and
  7. Gerard J. Mulder3
  1. Departments of 1Surgery (J.R., C.J.H.V.) and 2Medical Statistics (H.P.), 3 Leiden University Medical Center, and Division of Toxicology (G.J.M.), Leiden/Amsterdam Center for Drug Research, Leiden, The Netherlands; 4Faculty of Pharmacy (R.W.S, J.H.B.), Utrecht University, Utrecht, The Netherlands; and 5Department of Radiology (L.J.S.K.), Leiden University Medical Center/Netherlands Cancer Institute, Amsterdam, The Netherlands
  1. Dr. G. J. Mulder, Division of Toxicology, Leiden/Amsterdam Center for Drug Research, Leiden University, P.O. Box 9503, 2300 RA Leiden, The Netherlands. E-mail:g.mulder{at}lacdr.leidenuniv.nl
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Research ArticleGASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

Reduced Liver Uptake of Arterially Infused Melphalan during Retrograde Rat Liver Perfusion with Unaffected Liver Tumor Uptake

Joost Rothbarth, Rolf W. Sparidans, Jos H. Beijnen, Leo J. Schultze Kool, Hein Putter, Cornelis J. H. van de Velde and Gerard J. Mulder
Journal of Pharmacology and Experimental Therapeutics November 1, 2002, 303 (2) 736-740; DOI: https://doi.org/10.1124/jpet.102.037895
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