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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Differential Inhibition and Inactivation of Human CYP1 Enzymes bytrans-Resveratrol: Evidence for Mechanism-Based Inactivation of CYP1A2

Thomas K. H. Chang, Jie Chen and Wendy B. K. Lee
Journal of Pharmacology and Experimental Therapeutics December 2001, 299 (3) 874-882;

Article Information

vol. 299 no. 3 874-882
PubMed 
11714871
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 6, 2001
  • Accepted August 28, 2001
  • Published online December 1, 2001.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Thomas K. H. Chang,
  2. Jie Chen and
  3. Wendy B. K. Lee
  1. Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
  1. Dr. Thomas K. H. Chang, Faculty of Pharmaceutical Sciences, The University of British Columbia, 2146 East Mall, Vancouver, BC, V6T 1Z3 Canada. E-mail:tchang{at}unixg.ubc.ca
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Differential Inhibition and Inactivation of Human CYP1 Enzymes bytrans-Resveratrol: Evidence for Mechanism-Based Inactivation of CYP1A2

Thomas K. H. Chang, Jie Chen and Wendy B. K. Lee
Journal of Pharmacology and Experimental Therapeutics December 1, 2001, 299 (3) 874-882;
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