Research ArticleDrug Discovery and Translational Medicine
Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase Activating Peptide
Cristina Moldovan Loomis, Benjamin Dutzar, Ethan W Ojala, Lee Hendrix, Charlie Karasek, Michelle Scalley-Kim, Jenny Mulligan, Pei Fan, Jens Billgren, Vanessa Rubin, Heidi Boshaw, Gayle Kwon, Sam Marzolf, Erica Stewart, David Jurchen, Susan M. Pederson, Lisa Perrino McCulloch, Brian Baker, Roger K Cady, John A Latham, Dan Allison and Leon F Garcia-Martinez
Journal of Pharmacology and Experimental Therapeutics January 14, 2019, jpet.118.253443; DOI: https://doi.org/10.1124/jpet.118.253443
Cristina Moldovan Loomis
1 Alder Biopharmaceuticals;
Benjamin Dutzar
1 Alder Biopharmaceuticals;
Ethan W Ojala
1 Alder Biopharmaceuticals;
Lee Hendrix
1 Alder Biopharmaceuticals;
Charlie Karasek
1 Alder Biopharmaceuticals;
Michelle Scalley-Kim
1 Alder Biopharmaceuticals;
Jenny Mulligan
1 Alder Biopharmaceuticals;
Pei Fan
1 Alder Biopharmaceuticals;
Jens Billgren
1 Alder Biopharmaceuticals;
Vanessa Rubin
1 Alder Biopharmaceuticals;
Heidi Boshaw
1 Alder Biopharmaceuticals;
Gayle Kwon
1 Alder Biopharmaceuticals;
Sam Marzolf
1 Alder Biopharmaceuticals;
Erica Stewart
1 Alder Biopharmaceuticals;
David Jurchen
1 Alder Biopharmaceuticals;
Susan M. Pederson
1 Alder Biopharmaceuticals;
Lisa Perrino McCulloch
1 Alder Biopharmaceuticals;
Brian Baker
1 Alder Biopharmaceuticals;
Roger K Cady
1 Alder Biopharmaceuticals;
John A Latham
1 Alder Biopharmaceuticals;
Dan Allison
2 Alder BIopharmaceuticals
Leon F Garcia-Martinez
1 Alder Biopharmaceuticals;
Data Supplement
- Supplemental Figures -
Supplemental Figure 1. PACAP38, but not PACAP27 binds CHO-K1 cell surface.
Supplemental Figure 2. HC-030031 inhibits umbellulone-induced increase in facial temperature.