More articles from Drug Discovery and Translational Medicine

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Development of a High-Affinity Inhibitor of the Prostaglandin Transporter
Yuling Chi, Jaeki Min, Jean-Francois Jasmin, Michael P. Lisanti, Young-Tae Chang and Victor L. Schuster

Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 633-641; DOI: https://doi.org/10.1124/jpet.111.181354
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Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway
Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu and Xiufeng Pang

Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 403-411; DOI: https://doi.org/10.1124/jpet.111.181891
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Multimodal Biomarker Investigation on Efficacy and Mechanism of Action for the Mammalian Target of Rapamycin Inhibitor, Temsirolimus, in a Preclinical Mammary Carcinoma OncoMouse Model: A Translational Medicine Study in Support for Early Clinical Development
Xinkang Wang, Yutian Zhan, Lei Zhao, John Alvarez, Inder Chaudhary, Bin-Bing Zhou, Robert T. Abraham and Giora Z. Feuerstein

Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 421-429; DOI: https://doi.org/10.1124/jpet.111.185249
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Drug Targeting to Monocytes and Macrophages Using Esterase-Sensitive Chemical Motifs
Lindsey A. Needham, Alan H. Davidson, Lindsay J. Bawden, Andrew Belfield, Elisabeth A. Bone, Deborah H. Brotherton, Sam Bryant, Michael H. Charlton, Vanessa L. Clark, Stephen J. Davies, Alastair Donald, Francesca A. Day, David Krige, Valérie Legris, Joanne McDermott, Yvonne McGovern, Jo Owen, Sanjay R. Patel, Stéphane Pintat, Richard J. Testar, Graham M. A. Wells, David Moffat and Alan H. Drummond

Journal of Pharmacology and Experimental Therapeutics October 2011, 339 (1) 132-142; DOI: https://doi.org/10.1124/jpet.111.183640
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AZD9668: Pharmacological Characterization of a Novel Oral Inhibitor of Neutrophil Elastase
T. Stevens, K. Ekholm, M. Gränse, M. Lindahl, V. Kozma, C. Jungar, T. Ottosson, H. Falk-Håkansson, A. Churg, J. L. Wright, H. Lal and A. Sanfridson

Journal of Pharmacology and Experimental Therapeutics October 2011, 339 (1) 313-320; DOI: https://doi.org/10.1124/jpet.111.182139
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Novel N-1,2-Dihydroxypropyl Analogs of Lobelane Inhibit Vesicular Monoamine Transporter-2 Function and Methamphetamine-Evoked Dopamine Release
David B. Horton, Kiran B. Siripurapu, Guangrong Zheng, Peter A. Crooks and Linda P. Dwoskin

Journal of Pharmacology and Experimental Therapeutics October 2011, 339 (1) 286-297; DOI: https://doi.org/10.1124/jpet.111.184770
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Pharmacologic Inhibition of Ghrelin Receptor Signaling Is Insulin Sparing and Promotes Insulin Sensitivity
Kenneth A. Longo, Elizabeth K. Govek, Anna Nolan, Thomas McDonagh, Soratree Charoenthongtrakul, Derek J. Giuliana, Kristen Morgan, Jeffrey Hixon, Chaoseng Zhou, Bruce Kelder, John J. Kopchick, Jeffrey O. Saunders, Manuel A. Navia, Rory Curtis, Peter S. DiStefano and Brad J. Geddes

Journal of Pharmacology and Experimental Therapeutics October 2011, 339 (1) 115-124; DOI: https://doi.org/10.1124/jpet.111.183764
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Regulation of Ingestive Behaviors in the Rat by GSK1521498, a Novel μ-Opioid Receptor-Selective Inverse Agonist
Diane M. Ignar, Aaron S. Goetz, Kimberly Nichols Noble, Luz Helena Carballo, Andrea E. Stroup, Julie C. Fisher, Joyce A. Boucheron, Tracy A. Brainard, Andrew L. Larkin, Andrea H. Epperly, Todd W. Shearer, Scott D. Sorensen, Jason D. Speake and Jonathan D. Hommel

Journal of Pharmacology and Experimental Therapeutics October 2011, 339 (1) 24-34; DOI: https://doi.org/10.1124/jpet.111.180943
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In Vivo Pharmacology and Toxicology Evaluation of Polyethylene Glycol-Conjugated Interferon β-1a
Xiao Hu, Kenneth Olivier, Evelyne Polack, Mary Crossman, Katie Zokowski, Robert S. Gronke, Suezanne Parker, Zhaoyang Li, Ivan Nestorov, Darren P. Baker, Janet Clarke and Meena Subramanyam

Journal of Pharmacology and Experimental Therapeutics September 2011, 338 (3) 984-996; DOI: https://doi.org/10.1124/jpet.111.180661
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Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available Heat Shock Protein 90 Inhibitor in a Human Tumor Xenograft Mouse Model
Shinji Yamazaki, Leslie Nguyen, Sylvia Vekich, Zhongzhou Shen, Min-Jean Yin, Pramod P. Mehta, Pei-Pei Kung and Paolo Vicini

Journal of Pharmacology and Experimental Therapeutics September 2011, 338 (3) 964-973; DOI: https://doi.org/10.1124/jpet.111.181339

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