Dipeptidyl peptidase (DPP) IV inhibitors are probably beneficial for preventing diabetic
complication and modulating glucagon-like peptide-1 receptor (GLP-1R) expression. The aim of …

EVC is a novel protein mutated in the human chondroectodermal dysplasia Ellis-van Creveld
syndrome (EvC; OMIM: 225500). We have inactivated Evc in the mouse and show that Evc -…

Background Experiences and inflammatory mediators are fundamental in the provocation of
major depressive disorders (MDDs). We investigated the roles and mechanisms of inducible …

Depression is often preceded by exposure to stressful life events. Chronic stress causes
perturbations in the immune system, and up-regulates production of proinflammatory cytokines, …

Play benefits childhood development and well-being, and is a key factor in sustainable city
design. Though previous studies have examined the effects of various urban features on how …

Background Evc is essential for Indian Hedgehog (Hh) signalling in the cartilage growth
plate. The gene encoding Evc2 is in close proximity in divergent orientation to Evc and …

Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a new class of oral
medicines being developed for the treatment of anemia in chronic kidney disease (CKD) patients…

This paper discusses the challenges in Maintenance, Repair, and Operations (MRO) parts
inventory management and how Industry 4.0 technologies can be leveraged to address them. …

Hypertensive renal injury is a complication of hypertension. Cordyceps cicadae (C. cicadae)
is a traditional Chinese medicine used to treat chronic kidney diseases especially renal …

Background Chronic kidney disease (CKD) is an increasing public health issue. Anemia,
which is a complication of CKD, is associated with reduced quality of life and increased …