α-Synuclein has been implicated in the pathogenesis of many neurodegenerative diseases,
including Parkinson's disease and Alzheimer's disease. Although the function of α-synuclein …

Aim To study the protective effects of green tea (−)-epicatechin (EC) against the toxic effects
of streptozotocin (STZ), a selective β cell toxin, on pancreatic islets in vivo and in vitro. …

Cytokines that are released by infiltrating inflammatory cells around the pancreatic islets are
involved in the pathogenesis of type 1 diabetes mellitus. Specifically, interleukin-1β (IL-1β) …

The effects of fluoxetine (Prozac), a widely used antidepressant drug, on Kv1.3 stably expressed
in Chinese hamster ovary cells were examined using the whole-cell and excised inside-…

Phospholipase D (PLD) has been implicated in the signal transduction pathways initiated
by several mitogenic protein tyrosine kinases. We demonstrate for the first time that most …

Phospholipase D (PLD) has been suggested to play an important role in a variety of cellular
functions. PLD activity has been shown to be significantly elevated in many tumours and …

Background Proanthocyanidin is a polyphenolic bioflavonoid with known antioxidant activity.
Some flavonoids have a modulatory effect on [Ca 2+ ] i . Although proanthocyanidin extract …

Glucagon‐like peptide‐1 (GLP‐1) and its potent agonists have been widely studied in
pancreatic islet β‐cells. However, GLP‐1 receptors are present in many extrapancreatic tissues …

The interaction of bisindolylmaleimide (BIM), widely used as a specific protein kinase C (PKC)
inhibitor, with rat brain Kv1.5 (rKv1.5) channels stably expressed in Chinese hamster …

The KAI1/CD82 protein has been documented as the tumor metastasis suppressor in many
types of human cancers. KAI1/CD82 regulates cell motility and invasiveness; however, the …