Gemcitabine (2′,2′-difluorodeoxycytidine), a deoxycytidine analog, and erlotinib, an
epidermal growth factor receptor-tyrosine kinase inhibitor, are used clinically to treat patients with …

Emodin, a tyrosine kinase inhibitor, is a natural anthraquinone derivative found in the roots
and rhizomes of numerous plants; it exhibits an anticancer effect on many malignancies. The …

Pancreatic adenocarcinoma is an aggressive disease with a high mortality rate. In this study,
we have newly generated a monoclonal antibody (mAb), Pa65-2, which specifically binds …

Curcumin (diferuloylmethane), a phenolic compound obtained from the rhizome of Curcuma
longa, is known to have antiproliferative and antitumor properties. Thymidine …

Emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone derivative
found in the roots and rhizomes of numerous plants. It is a tyrosine kinase inhibitor and has …

Etoposide (VP-16), a topoisomerase II inhibitor, is an effective anticancer drug currently
used for the treatment of a wide range of cancers. Excision repair cross-complementary 1 (…

Curcumin (diferuloylmethane), a major active component of turmeric (Curcuma longa), has
been reported to suppress the proliferation of a wide variety of tumor cells. Rad51 is a key …

Thymidine phosphorylase (TP) is the rate-limiting enzyme for the activation of capecitabine (pro-drug
of fluorouracil), and as a useful predictor of tumor response to capecitabine-based …

Chemotherapy for advanced human non–small-cell lung cancer (NSCLC) includes platinum-containing
compound such as cisplatin in combination with a second- or third-generation …

Curcumin (diferuloylmethane), a phenolic compound obtained from the rhizome of Curcuma
longa, has been found to inhibit cell proliferation in various human cancer cell lines, …