The role of glial cells is to support and sustain proper neuronal function and microglia are
no exception to this. This viewpoint article emphasizes the fundamental interdependence of …

The present review summarizes recently acquired data in vivo, which support a role of CNS
microglia as a source of defense cells in the CNS capable of carrying out certain immune …

We have studied microglial morphology in the human cerebral cortex of two nondemented
subjects using high‐resolution LN‐3 immunohistochemistry. Several abnormalities in …

Microglial research has advanced considerably in recent decades yet has been constrained
by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2." …

Damage to the central nervous system (CNS) elicits the activation of both astrocytes and
microglia. This review is focused on the principal features that characterize the activation of …

A recently identified chemokine, fractalkine, is a member of the chemokine gene family, which
consists principally of secreted, proinflammatory molecules. Fractalkine is distinguished …

OX2 (CD200) is a broadly expressed membrane glycoprotein, shown here to be important
for regulation of the macrophage lineage. In mice lacking CD200, macrophage lineage cells, …

Microglia make up the innate immune system of the central nervous system and are key
cellular mediators of neuroinflammatory processes. Their role in central nervous system …

The past 20 years have seen a gain in knowledge on microglia biology and microglia functions
in disease that exceeds the expectations formulated when the microglia “immune network…

The role of microglial cells in the pathogenesis of Alzheimer’s disease (AD) neurodegeneration
is unknown. Although several works suggest that chronic neuroinflammation caused by …