Analytical procedures for quantification of peptides in pharmaceutical research by liquid chromatography–mass spectrometry

…, M Walden, S Schäfer, S Genz, WG Forssmann - Analytical and …, 2004 - Springer
Peptide quantification by liquid chromatography–mass spectrometry (LC–MS) combines the
high resolving power of reversed-phase (RP) chromatography with the excellent selectivity …

[HTML][HTML] LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

…, S Neitz, HJ Mägert, A Schulz, WG Forssmann… - FEBS letters, 2000 - Elsevier
We report the isolation and characterization of a novel human peptide with antimicrobial
activity, termed LEAP-1 (liver-expressed antimicrobial peptide). Using a mass spectrometric …

The renal urodilatin system: clinical implications

WG Forssmann, M Meyer… - Cardiovascular …, 2001 - academic.oup.com
A renal natriuretic peptide and the ‘renal urodilatin system’ were identified after the
observation that immunoassayable ANP in urine may not be identical to the circulating cardiac …

hBD‐1: a novel β‐defensin from human plasma

…, HJ Mägert, P Schulz-Knappe, WG Forssmann - FEBS …, 1995 - Wiley Online Library
We report the isolation and characterization of a novel peptide with significant sequence
homology to β‐defensins from human blood filtrate. The human β‐defensin‐1 (hBD‐1) is a short …

Human β‐defensin 4: a novel inducible peptide with a specific salt‐sensitive spectrum of antimicrobial activity

…, E Klüver, K Adermann, U Forssmann… - The FASEB …, 2001 - Wiley Online Library
β‐Defensins are antibiotic peptides involved in host defense at the epithelial surface. Three
human β‐defensins (hBDs)‐‐hBD‐1, hBD‐2, and hBD‐3‐‐have been identified so far. We …

[HTML][HTML] Semen-derived amyloid fibrils drastically enhance HIV infection

…, JC Grivel, L Margolis, OT Keppler, WG Forssmann… - Cell, 2007 - cell.com
Sexual intercourse is the major route of HIV transmission. To identify endogenous factors
that affect the efficiency of sexual viral transmission, we screened a complex peptide/protein …

Identification of a novel, multifunctional β-defensin (human β-defensin 3) with specific antimicrobial activity: Its interaction with plasma membranes of Xenopus …

…, A Krause, J Rodríguez-Jiménez, U Forssmann… - Cell and tissue …, 2001 - Springer
Previous studies have shown the implication of β-defensins in host defense of the human
body. The human β-defensins 1 and 2 (hBD-1, hBD-2) have been isolated by biochemical …

[HTML][HTML] Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide

…, D Wilhelm, H Lu, W Jing, S Jiang, WG Forssmann… - Cell, 2007 - cell.com
A variety of molecules in human blood have been implicated in the inhibition of HIV-1. However,
it remained elusive which circulating natural compounds are most effective in controlling …

Casocidin-I: a casein-αs2 derived peptide exhibits antibacterial activity

…, M Raida, K Adermann, HJ Mägert, WG Forssmann - FEBS letters, 1995 - Elsevier
Here we report the isolation and characterization of an antibacterial peptide from bovine
milk inhibiting the growth of Escherichia coli, and Staphylococcus carnosus. The primary …

Human milk provides peptides highly stimulating the growth of bifidobacteria

…, M Raida, HJ Mägert, WG Forssmann… - European Journal of …, 2002 - Wiley Online Library
The large intestine of breast‐fed infants is colonized predominantly by bifidobacteria, which
have a protective effect against acute diarrhea. In this study we report for the first time the …