There is no widely accepted quantitative method for evaluating the functional effects of
peripheral nerve damage in animals. In the present study, a method for evaluating sciatic nerve …

In order to determine if brain tissue grafts can provide functional input to recipient central
nervous system tissue, fetal rat dopamine-containing neurons were implanted adjacent to the …

High-throughput cDNA microarray technology allows for the simultaneous analysis of gene
expression levels for thousands of genes and as such, rapid, relatively simple methods are …

Cultured human embryonic stem cell (hESC) lines are an invaluable resource because they
provide a uniform and stable genetic system for functional analyses and therapeutic …

In this manuscript we report that human embryonic stem cells (hESCs) differentiated into
dopaminergic neurons when cocultured with PA6 cells. After 3 weeks of differentiation, …

Microarray studies can be used to examine expression levels for large numbers of genes
simultaneously and may be applied to identify genes involved in schizophrenia. A microarray …

The greatest therapeutic promise of human embryonic stem cells (hESC) is to generate
specialized cells to replace damaged tissue in patients suffering from various degenerative …

Using cDNA microarrays we have investigated gene expression patterns in brain regions of
patients with schizophrenia. A cDNA neuroarray, comprised of genes related to brain …

Transforming growth factor (TGF)β plays a role in injury repair in sites surrounding brain injury.
The present study tested the hypothesis that TGFβ1 and TGFβ2 levels in the postmortem …

Rats with unilateral lesions of substantia nigra pars compacta (SN), the area of the brain
containing most dopamine-containing neurones, are a widely recognized animal model of …