MTM1 mutations in X‐linked myotubular myopathy
…, SM Tanner, W Kress, V Schneider… - Human …, 2000 - Wiley Online Library
X‐linked myotubular myopathy (XLMTM; MIM# 310400) is a severe congenital muscle
disorder caused by mutations in the MTM1 gene. This gene encodes a dual‐specificity …
disorder caused by mutations in the MTM1 gene. This gene encodes a dual‐specificity …
[PDF][PDF] Pharmacological inhibition of integrin αvβ3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis
E Patsenker, Y Popov, F Stickel, V Schneider… - …, 2009 - Wiley Online Library
The vitronectin receptor integrin αvβ3 promotes angiogenesis by mediating migration and
proliferation of endothelial cells, but also drives fibrogenic activation of hepatic stellate cells (…
proliferation of endothelial cells, but also drives fibrogenic activation of hepatic stellate cells (…
Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis
M Neef, M Ledermann, H Saegesser, V Schneider… - Journal of …, 2006 - Elsevier
BACKGROUND/AIMS: Mammalian target of rapamycin (mTOR) signalling is central in the
activation of hepatic stellate cells (HSCs), the key source of extracellular matrix (ECM) in …
activation of hepatic stellate cells (HSCs), the key source of extracellular matrix (ECM) in …
Clonality and X-inactivation patterns in hematopoietic cell populations detected by the highly informative M27 beta DNA probe [see comments]
…, A von Rohr, B Borisch, L Theilkas, V Schneider… - 1994 - ashpublications.org
About 80% to 90% of females are informative for X- inactivation/methylation analysis with
the probe M27 beta, which would therefore seem attractive in assessing clonality in …
the probe M27 beta, which would therefore seem attractive in assessing clonality in …
Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis
E Patsenker, V Schneider, M Ledermann… - Journal of …, 2011 - Elsevier
BACKGROUND & AIMS: Recurrence of chronic hepatitis C and progressive fibrosis in liver
transplants is frequent and impairs both graft and patient survival. Whether or not the choice …
transplants is frequent and impairs both graft and patient survival. Whether or not the choice …
[HTML][HTML] Cannabinoid receptor type I modulates alcohol-induced liver fibrosis
…, G Millonig, A Agaimy, T Wissniowski, V Schneider… - Molecular …, 2011 - Springer
The cannabinoid system (CS) is implicated in the regulation of hepatic fibrosis, steatosis
and inflammation, with cannabinoid receptors 1 and 2 (CB1 and CB2) being involved in …
and inflammation, with cannabinoid receptors 1 and 2 (CB1 and CB2) being involved in …
Oral imatinib treatment reduces early fibrogenesis but does not prevent progression in the long term
M Neef, M Ledermann, H Saegesser, V Schneider… - Journal of …, 2006 - Elsevier
BACKGROUND/AIMS: Transactivated hepatic stellate cells (HSCs) represent the key
source of extra cellular matrix (ECM) in fibrotic liver. Imatinib, a potent inhibitor of the PDGF …
source of extra cellular matrix (ECM) in fibrotic liver. Imatinib, a potent inhibitor of the PDGF …
Long-term treatment of bile duct-ligated rats with rapamycin (sirolimus) significantly attenuates liver fibrosis: analysis of the underlying mechanisms
…, M Neef, M Unternährer, V Schneider… - … of Pharmacology and …, 2005 - ASPET
Rapamycin is an immunosuppressant with antiproliferative properties. We investigated
whether rapamycin treatment of bile duct-ligated (BDL) rats is capable of inhibiting liver fibrosis …
whether rapamycin treatment of bile duct-ligated (BDL) rats is capable of inhibiting liver fibrosis …
Genetic variants of the TbAT1 adenosine transporter from African trypanosomes in relapse infections following melarsoprol therapy
E Matovu, F Geiser, V Schneider, P Mäser… - Molecular and …, 2001 - Elsevier
We have analyzed the TbAT1 gene, which codes for the P2 adenosine transporter, from
Trypanosoma brucei field isolates to investigate a possible link between the presence of …
Trypanosoma brucei field isolates to investigate a possible link between the presence of …
Two buffer PAGE system-based SSCP/HD analysis: a general protocol for rapid and sensitive mutation screening in cystic fibrosis and any other human genetic …
S Liechti-Gallati, V Schneider, D Neeser… - European Journal of …, 1999 - nature.com
The large size of many disease genes and the multiplicity of mutations complicate the design
of an adequate assay for the identification of disease-causing variants. One of the most …
of an adequate assay for the identification of disease-causing variants. One of the most …