… In addition, recent evidence reviewed here by Ulrich Quast suggests that the K + channel
openers possess further mechanisms of vasorelaxation not linked to the opening of …

Insulin secretagogues (sulfonylureas and glinides) increase insulin secretion by closing the
ATP-sensitive K + channel (K ATP channel) in the pancreatic β-cell membrane. K ATP …

Total Body Irradiation (TBI) is one main component in the interdisciplinary treatment of widely
disseminated malignancies predominantly of haematopoietic diseases. Combined with …

In treatment of acute leukaemia and other disseminated diseases, high dose total body
irradiation (TBI)combined with intensive chemotherapy and bone marrow transplantation (BMT) …

ATP‐sensitive K + channels are composed of pore‐forming subunits Kir6.2 and of sulphonylurea
receptors (SURs); the latter are the target of the hypoglycaemic sulphonylureas like …

Potassium channel opening is a physiological mechanism which excitable cells exploit to
maintain or restore their resting state. Thus drugs that open vascular potassium channels have …

In the treatment of acute leukemias, high doses of chemotherapy and total‐body irradiation (TBI)
are used prior to bone marrow transplantation. However, the doses needed equal or …

Planar bilayer membranes containing functional acetylcholine receptor were formed from
vesicles of Torpedo marmorata electric organ without extracting the acetylcholine receptor from …

The K+ channel openers, including cromakalim, pinacidil, minoxidil sulfate, diazoxide, and
nicorandil, form a chemically heterogeneous group of compounds, which relax smooth …

K ATP channels are heteromeric complexes of inwardly rectifying K + channel subunits and
sulfonylurea receptors (SURs). SUR2A and SUR2B, which differ within the carboxyl terminal …