[HTML][HTML] Membranous nephropathy: a review on the pathogenesis, diagnosis, and treatment
…, WC Chiang, YM Chen, KD Wu, TJ Tsai - Journal of the Formosan …, 2015 - Elsevier
In adults, membranous nephropathy (MN) is a major cause of nephrotic syndrome. However,
the etiology of approximately 75% of MN cases is idiopathic. Secondary causes of MN are …
the etiology of approximately 75% of MN cases is idiopathic. Secondary causes of MN are …
[HTML][HTML] Platelet-derived growth factor receptor signaling activates pericyte–myofibroblast transition in obstructive and post-ischemic kidney fibrosis
…, WC Chiang, J Shen, YM Chen, KD Wu, TJ Tsai… - Kidney international, 2011 - Elsevier
Pericytes are the major source of scar-producing myofibroblasts following kidney injury;
however, the mechanisms of this transition are unclear. To clarify this, we examined Collagen 1 (…
however, the mechanisms of this transition are unclear. To clarify this, we examined Collagen 1 (…
[HTML][HTML] Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis
…, F Kuhnert, CJ Kuo, YM Chen, KD Wu, TJ Tsai… - The American journal of …, 2011 - Elsevier
Microvascular pericytes and perivascular fibroblasts have recently been identified as the
source of scar-producing myofibroblasts that appear after injury of the kidney. We show that …
source of scar-producing myofibroblasts that appear after injury of the kidney. We show that …
[HTML][HTML] Transforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis
…, TH Wu, GR Linn, H Ling, KD Wu, TJ Tsai… - The American journal of …, 2013 - Elsevier
Pericytes have been identified as the major source of precursors of scar-producing
myofibroblasts during kidney fibrosis. The underlying mechanisms triggering pericyte-myofibroblast …
myofibroblasts during kidney fibrosis. The underlying mechanisms triggering pericyte-myofibroblast …
[HTML][HTML] Acute-on-chronic kidney injury at hospital discharge is associated with long-term dialysis and mortality
…, JY Wang, TW Kao, GH Young, PR Tsai, HB Tsai… - Kidney international, 2011 - Elsevier
Existing chronic kidney disease (CKD) is among the most potent predictors of postoperative
acute kidney injury (AKI). Here we quantified this risk in a multicenter, observational study of …
acute kidney injury (AKI). Here we quantified this risk in a multicenter, observational study of …
Rate of decline of residual renal function is associated with all-cause mortality and technique failure in patients on long-term peritoneal dialysis
…, HF Chuang, KY Hung, KD Wu, TJ Tsai - Nephrology Dialysis …, 2009 - academic.oup.com
Background. Residual renal function (RRF) at the initiation of peritoneal dialysis (PD) therapy
can predict patient outcome. However, RRF declines with time at variable rates in different …
can predict patient outcome. However, RRF declines with time at variable rates in different …
Pentoxifylline attenuates tubulointerstitial fibrosis by blocking Smad3/4-activated transcription and profibrogenic effects of connective tissue growth factor
…, WC Chiang, CF Lai, KD Wu, TJ Tsai - Journal of the …, 2005 - journals.lww.com
Pentoxifylline (PTX) is a potent inhibitor of connective tissue growth factor (CTGF), but its
underlying mechanism is poorly understood. Here, it was demonstrated that PTX inhibited not …
underlying mechanism is poorly understood. Here, it was demonstrated that PTX inhibited not …
[HTML][HTML] Sexual dysfunction in female hemodialysis patients: a multicenter study
…, CC Yang, DM Tsai, PY Chen, CS Liao, TJ Tsai… - Kidney international, 2005 - Elsevier
… Yang , Yu-Chin Huang , Kwan-Dun Wu , Ming-Shiou Wu , Yih-Ron Lien , Chin-Ching Yang
, Dong-Ming Tsai , Pei-Yuan Chen , Cheng-Shiung Liao , Tun-Jun Tsai , Wang-Yu Chen …
, Dong-Ming Tsai , Pei-Yuan Chen , Cheng-Shiung Liao , Tun-Jun Tsai , Wang-Yu Chen …
[HTML][HTML] Impact of timing of renal replacement therapy initiation on outcome of septic acute kidney injury
Introduction Sepsis is the leading cause of acute kidney injury (AKI) in critical patients. The
optimal timing of initiating renal replacement therapy (RRT) in septic AKI patients remains …
optimal timing of initiating renal replacement therapy (RRT) in septic AKI patients remains …
Comparison of residual renal function in patients undergoing twice‐weekly versus three‐times‐weekly haemodialysis
…, TS CHU, SL LIN, YM CHEN, TUNJUN TSAI… - …, 2009 - Wiley Online Library
Aim: Patients with end‐stage renal disease (ESRD) often start long‐term haemodialysis (HD)
thrice weekly, regardless of the level of residual renal function (RRF). In this study, we …
thrice weekly, regardless of the level of residual renal function (RRF). In this study, we …