In abstinent alcoholics, stress induces negative affect—a response linked to craving and
relapse. In rats, repeated stresses at weekly intervals before 5-day ethanol diet sensitize …

Previous investigations demonstrated that repeated stresses before an ethanol exposure
sensitize ethanol withdrawal-induced anxiety-like behavior (‘anxiety’). In addition to activating …

The bed nucleus of the stria terminalis (BNST) is a critical region for alcohol/drug-induced
negative affect and stress-induced reinstatement. NMDA receptor (NMDAR)-dependent …

In current models, learning the relationship between environmental stimuli and the outcomes
of actions involves both stimulus-driven and goal-directed systems, mediated in part by the …

Stress has been shown to facilitate ethanol withdrawal-induced anxiety. Defining neurobiological
mechanisms through which stress has such actions is important given the associated …

Background: This work was conducted in an effort to establish an oral intake model system
in which the effects of ethanol insult that occur during early stages of embryogenesis can be …

Background: Repeated ethanol withdrawal sensitizes anxiety‐like behavior in adult rats and
causes anxiety‐like behavior and decreased seizure thresholds in adolescent rats. Current …

Adolescent alcohol use is the strongest predictor for alcohol use disorders. In rodents,
adolescents have distinct responses to acute ethanol, and prolonged alcohol exposure during …

Rationale Stress may elevate ethanol drinking and anxiety associated with ethanol drinking.
Studies to identify relevant neurobiological substrates are needed. Objective To assess …

Adolescent alcohol use is one of the strongest predictors for the development of an alcohol
use disorder (AUD). Notably, this period of risk coincides with the development of affective …