Axon-sparing lesion of the preoptic area enhances receptivity and diminishes proceptivity among components of female rat sexual behavior

Y Hoshina, T Takeo, K Nakano, T Sato… - Behavioural brain …, 1994 - Elsevier
Stereotaxic infusion of ibotenic acid deleted neurons in the medial preoptic area (POA) in the
ovariectomized female rats. A well-circumscribed lesion was infiltrated by astrocytes; local …

Hormone-induced secretory and nuclear translocation of calmodulin: oscillations of calmodulin concentration with the nucleus as an integrator

M Craske, T Takeo, O Gerasimenko… - Proceedings of the …, 1999 - National Acad Sciences
Many important enzyme activities are regulated by Ca 2+ -dependent interactions with
calmodulin (CaM). Some of the most important targets for CaM action are in the nucleus, and Ca 2…

Suppression of the lordosis reflex of female rats by efferents of the medial preoptic area

T Takeo, Y Chiba, Y Sakuma - Physiology & behavior, 1993 - Elsevier
In freely moving, estrogen- and progesterone-treated ovariectomized female rats, electrical
stimulation of the medial preoptic area, which had been isolated dorsally from the septum by …

2-Aminoethoxydiphenyl borate modulates kinetics of intracellular Ca2+ signals mediated by inositol 1, 4, 5-trisphosphate-sensitive Ca2+ stores in single pancreatic …

J Wu, N Kamimura, T Takeo, S Suga, M Wakui… - Molecular …, 2000 - ASPET
Regulation of the kinetics of intracellular Ca 2+ signals with a novel, membrane-penetrable,
inositol 1,4,5-trisphosphate (InsP 3 ) receptor/Ca 2+ channel modulator, 2-amino-…

GLP-I(7–36) Amide Augments Ba2+ Current Through L-Type Ca2+ Channel of Rat Pancreatic β-Cell in a cAMP-Dependent Manner

S Suga, T Kanno, K Nakano, T Takeo, Y Dobashi… - Diabetes, 1997 - Am Diabetes Assoc
The whole-cell patch-clamp method was used to examine the effect of glucagon-like peptide
I (GLP-I)(7–36) amide on the activation process of L-type Ca 2+ channels of rat pancreatic β-…

Augmented β cell loss and mitochondrial abnormalities in sucrose-fed GK rats

H Mizukami, R Wada, M Koyama, T Takeo, S Suga… - Virchows Archiv, 2008 - Springer
Progressive decline of islet β cell mass is a hallmark of type 2 diabetes, where nutritional
insults are invoked in the pathologic process. Its detailed mechanisms are, however, …

Opposite effects of two resveratrol (trans-3, 5, 4′-trihydroxystilbene) tetramers, vitisin A and hopeaphenol, on apoptosis of myocytes isolated from adult rat heart

…, K Kanemaru, C Sugimoto, M Suzuki, T Takeo… - … of Pharmacology and …, 2009 - ASPET
It has been reported that resveratrol (trans-3,5,4′-trihydroxystilbene) from Vitis plants has
various cardioprotective effects. Vitis plants also include various resveratrol tetramers. The …

Diametrically opposite effects of estrogen on the excitability of female rat medial and lateral preoptic neurons with axons to the midbrain locomotor region

T Takeo, Y Sakuma - Neuroscience research, 1995 - Elsevier
Electrical stimulation of the midbrain locomotor region (MLR) in 76 ovariectomized, urethan-anesthetized
female rats elicited antidromic action potentials in 252 preoptic neurons. …

[HTML][HTML] Hydrogen peroxide mobilizes Ca2+ through two distinct mechanisms in rat hepatocytes

H Sato, T Takeo, Q Liu, K Nakano, T Osanai… - Acta Pharmacologica …, 2009 - nature.com
Aim: Hydrogen peroxide (H 2 O 2) is produced during liver transplantation. Ischemia/reperfusion
induces oxidation and causes intracellular Ca 2+ overload, which harms liver cells. Our …

Intracellular Ca2+ Modulation of ATP-Sensitive K+ Channel Activity in Acetylcholine-Induced Activation of Rat Pancreatic β-Cells

K Nakano, S Suga, T Takeo, Y Ogawa, T Suda… - …, 2002 - academic.oup.com
We investigated the mechanism by which acetylcholine (ACh) regulates insulin secretion from
rat pancreatic β-cells. In an extracellular solution with 5.5 mm glucose, ACh increased the …