Accelerated induction of two-kidney hypertension in rats and renin-angiotensin sensitivity

TW Skulan, AC Brousseau, KA Leonard - Circulation Research, 1974 - Am Heart Assoc
Studies were performed to substantiate the hypothesis that a physiological change, apart
from the rise in blood pressure, occurs in two-kidney hypertensive rats. Both the slow …

[PDF][PDF] Effects of adrenalectomy and desoxycorticosterone on stop-flow patterns of sodium and potassium in the rat

HE Williamson, TW Skulan, FE Shideman - Journal of Pharmacology and …, 1961 - Citeseer
METHODS. The principles and methodology of “stop-flow” analysis of renal tubular transport
mechanisms in the dog have been de8dribed by Malvin et at.(1958). The technic, as we …

Effects of dinitrophenol and cyanide on TPAH and Na reabsorption

IM Weiner, L Roth, TW Skulan - American Journal of …, 1971 - journals.physiology.org
METHODS Mongrel dogs of both sexes (11.5-15 kg) were anesthetized with sodium pentobarbital,
30 mg/kg. In each experiment the animal received an intravenous infusion containing …

Amine functions of reduced basicity. Hypoglycemic and natriuretic. alpha.-alkoxybenzylamidoximes, amidines, and cycloamidines

…, HR Harding, GO Potts, TW Skulan - Journal of Medicinal …, 1974 - ACS Publications
The introduction of-alkoxybenzyl groups into carboxamidoximes, carboxamidines, 2-imidazolines,
1, 4, 5, 6-tetrahydropyrimidines, and 4, 5, 6, 7-tetrahydro-lH-l, 3-diazepines …

[PDF][PDF] Natriuretic and antiglycogenic activities of a series of symmetrical triazine and pteridine derivatives

TW Skulan, FE Shideman - Journal of Pharmacology and Experimental …, 1965 - Citeseer
METHODS AND MATERIALS. Natriuretic and antiglycogenic potencies for each of the triazine
derivatives were determined from the ratios of equiactive doses of the standard compound …

Preliminary observations on the toxicity of the hydrochloride and acetate salts of mafenide (sulfamylon r)

TW Skulan, JO Hoppe - Life Sciences, 1966 - Elsevier
Mafenide acetate was found to produce less metabolic acidosis and to be significantly less
toxic than mafenide hydrochloride following intravenous administration in experimental …

Geometric and electronic structure/function correlations in non-heme iron enzymes

…, SK Lee, N Lehnert, F Neese, AJ Skulan… - Chemical …, 2000 - ACS Publications
In recent years, significant progress has been made in understanding the geometric and
electronic structures of the active sites of non-heme iron enzymes and the contributions of these …

Dielectrophoretic manipulation of particles and cells using insulating ridges in faceted prism microchannels

LM Barrett, AJ Skulan, AK Singh… - Analytical …, 2005 - ACS Publications
This paper presents a novel device for the dielectrophoretic manipulation of particles and cells.
A two-level isotropic etch of a glass substrate was used to create three-dimensional ridge-…

Calcium isotope fractionation between soft and mineralized tissues as a monitor of calcium use in vertebrates

J Skulan, DJ DePaolo - Proceedings of the National …, 1999 - National Acad Sciences
Calcium from bone and shell is isotopically lighter than calcium of soft tissue from the same
organism and isotopically lighter than source (dietary) calcium. When measured as the 44 Ca…

Natural calcium isotopic composition of urine as a marker of bone mineral balance

J Skulan, T Bullen, AD Anbar, JE Puzas… - Clinical …, 2007 - academic.oup.com
Background: We investigated whether changes in the natural isotopic composition of calcium
in human urine track changes in net bone mineral balance, as predicted by a model of …