User profiles for T R Insel

Thomas R. Insel

Director, NIMH
Verified email at mail.nih.gov
Cited by 99068

[PDF][PDF] A neurobiological basis of social attachment

TR Insel - American Journal of Psychiatry, 1997 - Citeseer
Insel TR: Regional changes in brain oxytocin receptors … Insel TR: Ontogeny of oxytocin
receptors in rat forebrain: a quantitative study. Synapse 1989; 4:259–266 75. Winslow JT, Insel TR

[HTML][HTML] Rethinking schizophrenia

TR Insel - Nature, 2010 - nature.com
How will we view schizophrenia in 2030? Schizophrenia today is a chronic, frequently disabling
mental disorder that affects about one per cent of the world’s population. After a century …

The neurobiology of attachment

TR Insel, LJ Young - Nature Reviews Neuroscience, 2001 - nature.com
It is difficult to think of any behavioural process that is more intrinsically important to us than
attachment. Feeding, sleeping and locomotion are all necessary for survival, but humans are, …

[HTML][HTML] The genotype-tissue expression (GTEx) project

…, MS Guyer, C Ng, A Abdallah, D Colantuoni, TR Insel… - Nature …, 2013 - nature.com
Genome-wide association studies have identified thousands of loci for common diseases,
but, for the majority of these, the mechanisms underlying disease susceptibility remain …

[HTML][HTML] Toward the future of psychiatric diagnosis: the seven pillars of RDoC

BN Cuthbert, TR Insel - BMC medicine, 2013 - Springer
Background Current diagnostic systems for mental disorders rely upon presenting signs
and symptoms, with the result that current definitions do not adequately reflect relevant …

[HTML][HTML] Grand challenges in global mental health

PY Collins, V Patel, SS Joestl, D March, TR Insel… - Nature, 2011 - nature.com
A consortium of researchers, advocates and clinicians announces here research priorities
for improving the lives of people with mental illness around the world, and calls for urgent …

The NIMH research domain criteria (RDoC) project: precision medicine for psychiatry

TR Insel - American journal of psychiatry, 2014 - Am Psychiatric Assoc
Johnson’s pessimism notwithstanding, over the past five decades biomedical scientists have
made extraordinary progress, discovering causes and finding cures for both infectious and …

Social amnesia in mice lacking the oxytocin gene

…, LJ Young, EF Hearn, MM Matzuk, TR Insel… - Nature …, 2000 - nature.com
The development of social familiarity in rodents depends predominantly on olfactory cues and
can critically influence reproductive success 1, 2. Researchers have operationally defined …

[PDF][PDF] The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior

TR Insel - Neuron, 2010 - cell.com
Social neuroscience is rapidly exploring the complex territory between perception and
action where recognition, value, and meaning are instantiated. This review follows the trail of …

Oxytocin in the medial amygdala is essential for social recognition in the mouse

JN Ferguson, JM Aldag, TR Insel… - Journal of …, 2001 - Soc Neuroscience
Oxytocin (OT) knock-out mice fail to recognize familiar conspecifics after repeated social
exposures, despite normal olfactory and spatial learning abilities. OT treatment fully restores …