Chronic Ethanol Intoxication Induces Differential Effects on GABAA and NMDA Receptor Function in the Rat Brain

…, G Colombo, P Follesa, T Cuccheddu… - Alcoholism: Clinical …, 1993 - Wiley Online Library
The effect of long‐term treatment with ethanol was investigated on the function of γ‐aminobutyric
acid A (GABA A ) and N‐methyl‐d‐as‐partic acid (NMDA) receptors. Rats were …

Neurosteroids in the brain of handling-habituated and naive rats: effect of CO2 inhalation

…, G Roscetti, M Trabucchi, T Cuccheddu… - European journal of …, 1994 - Elsevier
In rats habituated to the manipulation that precedes killing (handling-habituated) the
cerebral cortical concentrations of pregnenolone and progesterone were significantly lower (−57% …

Carbon dioxide inhalation reduces the function of GABAA receptors in the rat brain

E Sanna, T Cuccheddu, M Serra, A Concas… - European journal of …, 1992 - Elsevier
The effect of CO 2 inhalation on the function of the GABA A -coupled chloride channel was
evaluated in rat brain. This treatment decreased the capability of GABA to stimulate 36 Cl − …

Proconflict effect of carbon dioxide inhalation in rats

T Cuccheddu, S Floris, M Serra, ML Porceddu… - Life sciences, 1995 - Elsevier
The effect of brief inhalation of carbon dioxide (CO 2 ) was studied in a conflict situation (Vogel
test) in the rat. This treatment, which inhibits γ-aminobutyric acid (GABA)-mediated …

Carbon dioxide inhalation, stress and anxiogenic drugs reduce the function of GABAA receptor complex in the rat brain

A Concas, E Sanna, T Cuccheddu, M Paola - Progress in Neuro …, 1993 - Elsevier
The effect of different stressful stimuli on the function of the GABA A -ionophore receptor
complex was evaluated by measuring the binding of 35 S-TBPS to the chloride channel …

Chronic ethanol intoxication enhances [3H] CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum

A Concas, MP Mascia, T Cuccheddu, S Floris… - Pharmacology …, 1996 - Elsevier
The effects of acute and chronic treatment with ethanol on the function of A 1 adenosine
receptor in the rat cerebellar cortex were investigated. Acute administration of ethanol (0.5–5 g/…

The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines

…, M Serra, G Santoro, E Maciocco, T Cuccheddu… - Naunyn-Schmiedeberg's …, 1994 - Springer
The effects of the cyclopyrrolones zopiclone and suriclone on the function of the central γ-aminobutyric
acid type A (GABA A A) receptor complex in mouse brain were evaluated both in …

Chronic administration of an anticonvulsant dose of imidazenil fails to induce tolerance of GABAA receptor function in mice

…, M Serra, C Motzo, P Giusti, T Cuccheddu… - European journal of …, 1994 - Elsevier
The ability of an anticonvulsant dose (0.1 mg/kg ip) of imidazenil, a new partial agonist of
benzodiazepine receptors, to antagonize the convulsions and the increase in t-[ 35 S]…

[PDF][PDF] Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor …

…, CA Ghiani, C Motzo, T Cuccheddu… - … of Pharmacology and …, 1994 - researchgate.net
The imidazobenzodiazepine 6-(2-bromophenyl)-8-fluoro-4H-imi-dazo-[1, 5-a][1, 4]
benzodiazepine-3-carboxamide(imidazenil) is a new anxolytic and anticonvulsant lEgend of the …

2-CHLORO-N6-CYCLOPENTYLADENOSINE (CCPA), AN ADENOSINE A1 RECEPTOR AGONIST, SUPPRESSES ETHANOL WITHDRAWAL SYNDROME IN RATS

A Concas, T CUCCHEDDU, S FLORIS… - Alcohol and …, 1994 - academic.oup.com
The ability of 2-chloro-N 6 -cyclopentyladenosine (CCPA) to suppress ethanol withdrawal
syndrome was tested in male rats rendered physically dependent on ethanol by intragastric …