User profiles for Simona Dedoni
Simona DedoniUniversità di Cagliari Verified email at unica.it Cited by 925 |
[HTML][HTML] K18-and CAG-hACE2 transgenic mouse models and SARS-CoV-2: implications for neurodegeneration research
S Dedoni, V Avdoshina, C Camoglio, C Siddi, W Fratta… - Molecules, 2022 - mdpi.com
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a
global pandemic that might lead to very serious consequences. Notably, mental status …
global pandemic that might lead to very serious consequences. Notably, mental status …
The HIV protein gp120 alters mitochondrial dynamics in neurons
Neurotoxicity of human immunodeficiency virus-1 (HIV) includes synaptic simplification and
neuronal apoptosis. However, the mechanisms of HIV-associated neurotoxicity remain …
neuronal apoptosis. However, the mechanisms of HIV-associated neurotoxicity remain …
Interferon‐β induces apoptosis in human SH‐SY5Y neuroblastoma cells through activation of JAK–STAT signaling and down‐regulation of PI3K/Akt pathway
J. Neurochem. (2010) 115, 1421–1433. Abstract Type I interferons (IFNs) are known to
cause neuropsychiatric side effects, which have been proposed to be mediated by either …
cause neuropsychiatric side effects, which have been proposed to be mediated by either …
The orphan G‐protein‐coupled receptor 75 signaling is activated by the chemokine CCL 5
The chemokine CCL 5 prevents neuronal cell death mediated both by amyloid β, as well as
the human immunodeficiency virus viral proteins gp120 and Tat. Because CCL 5 binds to …
the human immunodeficiency virus viral proteins gp120 and Tat. Because CCL 5 binds to …
[HTML][HTML] Anaplastic lymphoma kinase receptor: possible involvement in anorexia nervosa
S Dedoni, M Scherma, C Camoglio, C Siddi, W Fratta… - Nutrients, 2023 - mdpi.com
The pathophysiology of Anorexia Nervosa (AN) has not been fully elucidated. Anaplastic
lymphoma kinase (ALK) receptor is a protein-tyrosine kinase mainly known as a key oncogenic …
lymphoma kinase (ALK) receptor is a protein-tyrosine kinase mainly known as a key oncogenic …
Activation of nociceptin/orphanin FQ‐NOP receptor system inhibits tyrosine hydroxylase phosphorylation, dopamine synthesis, and dopamine D1 receptor signaling …
MC Olianas, S Dedoni, M Boi… - Journal of …, 2008 - Wiley Online Library
Nociceptin/orphanin FQ (N/OFQ) has been reported to inhibit dopamine (DA) release in basal
ganglia mainly by acting on NOP receptors in substantia nigra and ventral tegmental area. …
ganglia mainly by acting on NOP receptors in substantia nigra and ventral tegmental area. …
Direct agonist activity of tricyclic antidepressants at distinct opioid receptor subtypes
Tricyclic antidepressants (TCAs) have been reported to interact with the opioid system, but
their pharmacological activity at opioid receptors has not yet been elucidated. In the present …
their pharmacological activity at opioid receptors has not yet been elucidated. In the present …
Downregulation of TrkB expression and signaling by valproic acid and other histone deacetylase inhibitors
S Dedoni, L Marras, MC Olianas, A Ingianni… - Journal of Pharmacology …, 2019 - ASPET
Valproic acid (VPA) has been shown to regulate the levels of brain-derived neurotrophic factor
(BDNF), but it is not known whether this drug can affect the neuronal responses to BDNF. …
(BDNF), but it is not known whether this drug can affect the neuronal responses to BDNF. …
Cannabinoid CB1 and CB2 receptors differentially regulate TNF-α-induced apoptosis and LPA1-mediated pro-survival signaling in HT22 hippocampal cells
Aims The aim of the study was to investigate the interaction between cannabinoid CB 1 /CB
2 and lysophosphatidic acid (LPA) receptors in controlling neuronal signaling and fate. …
2 and lysophosphatidic acid (LPA) receptors in controlling neuronal signaling and fate. …
Type I interferons impair BDNF‐induced cell signaling and neurotrophic activity in differentiated human SH‐SY5Y neuroblastoma cells and mouse primary cortical …
S Dedoni, MC Olianas, A Ingianni… - Journal of …, 2012 - Wiley Online Library
Type I interferons impair BDNF‐induced cell signaling and neurotrophic activity in differentiated
human SH‐SY5Y neuroblastoma cells and mouse primary cortical neurons - Dedoni - …
human SH‐SY5Y neuroblastoma cells and mouse primary cortical neurons - Dedoni - …