Background— Serotonin (5-hydroxytryptamine [5-HT]), released by activated platelets during
cardiac ischemia, is metabolized by the mitochondrial enzyme monoamine oxidase A (MAO…

To investigate the potential involvement of the nitric oxide (NO) pathway in colorectal
carcinogenesis, we correlated the expression and the activity of inducible nitric oxide synthase (…

The hormone relaxin (RLX) is produced by the heart and has beneficial actions on the
cardiovascular system. We previously demonstrated that RLX stimulates mouse neonatal …

Mesenchymal stromal cells (MSCs) are the leading cell candidates in the field of regenerative
medicine. These cells have also been successfully used to improve skeletal muscle repair/…

The possibility to induce myocardial regeneration by the activation of resident cardiac stem
cells (CSCs) has raised great interest. However, to propose endogenous CSCs as …

The hormone relaxin has been shown to cause coronary vasodilation and to prevent
ischemia/reperfusion‐induced cardiac injury in rodents. This study provides evidence that relaxin, …

In the post‐infarcted heart, grafting of precursor cells may partially restore heart function but
the improvement is modest and the mechanisms involved remain to be elucidated. Here, we …

In animal models of inflammation, the pregnancy hormone relaxin was shown to reduce the
recruitment of leukocytes, especially neutrophils, in inflamed tissues. The current study was …

In animal models, the cardiotropic hormone relaxin has been shown to protect the heart
against ischemia and reperfusion‐induced damage, acting by multiple mechanisms that …

Although mechanisms involved in the pathogenesis of asthma remain unclear, roles for
oxidative/nitrosative stress, epithelial cell apoptosis, and airway inflammation have been …