User profiles for Silja Meier
 | Silja MeierDepartment of Pharmacology, University of Oslo and Oslo University Hospital Verified email at medisin.uio.no Cited by 574 |
The influence of scoring method on variability in results obtained with the comet assay
As part of a project to develop high throughput versions of the comet assay (single cell gel
electrophoresis), with a consequent need for more efficient scoring, we have compared the …
electrophoresis), with a consequent need for more efficient scoring, we have compared the …
High-throughput comet assay using 96 minigels
KB Gutzkow, TM Langleite, S Meier, A Graupner… - …, 2013 - academic.oup.com
The single-cell gel electrophoresis—the comet assay—has proved to be a sensitive and
relatively simple method that is much used in research for the analysis of specific types of DNA …
relatively simple method that is much used in research for the analysis of specific types of DNA …
Twelve-gel slide format optimised for comet assay and fluorescent in situ hybridisation
The comet assay is widely used to measure DNA damage and repair in basic research,
genotoxicity testing and human biomonitoring. The conventional format has 1 or 2 gels on a …
genotoxicity testing and human biomonitoring. The conventional format has 1 or 2 gels on a …
A comparative performance test of standard, medium-and high-throughput comet assays
A serious limitation of the conventional comet assay (single cell gel electrophoresis) is the
restriction on the number of samples that can be processed in one experiment, imposed by …
restriction on the number of samples that can be processed in one experiment, imposed by …
PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
S Meier, KW Andressen, JM Aronsen, I Sjaastad… - European journal of …, 2017 - Elsevier
We have previously shown that the natriuretic peptide receptor B (NPR-B) agonist C-type
natriuretic peptide (CNP) enhances cyclic adenosine 3,5-monophosphate (cAMP)-mediated …
natriuretic peptide (CNP) enhances cyclic adenosine 3,5-monophosphate (cAMP)-mediated …
Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle
LR Moltzau, JM Aronsen, S Meier, J Skogestad… - … of Pharmacology and …, 2014 - ASPET
We previously found a negative inotropic (NIR) and positive lusitropic response (LR) to C-type
natriuretic peptide (CNP) in the failing heart ventricle. In this study, we investigated and …
natriuretic peptide (CNP) in the failing heart ventricle. In this study, we investigated and …
CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors
…, D Arunthavarajah, NC Surdo, S Meier… - Cardiovascular …, 2022 - academic.oup.com
Aims Guanylyl cyclase-B (GC-B; natriuretic peptide receptor-B, NPR-B) stimulation by C-type
natriuretic peptide (CNP) increases cGMP and causes a lusitropic and negative inotropic …
natriuretic peptide (CNP) increases cGMP and causes a lusitropic and negative inotropic …
Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium
LR Moltzau, S Meier, JM Aronsen, F Afzal… - Naunyn-Schmiedeberg's …, 2014 - Springer
Recently, we showed C-type natriuretic peptide (CNP)-induced negative inotropic (NIR) and
positive lusitropic response (LR) in failing rat heart. We wanted to study whether, and if so, …
positive lusitropic response (LR) in failing rat heart. We wanted to study whether, and if so, …
[HTML][HTML] Enhancement of cAMP-mediated inotropic responses by CNP is regulated differently by PDE2 in normal and failing hearts
S Meier, KW Andressen, JM Aronsen, I Sjaastad… - BMC Pharmacology and …, 2015 - Springer
Background Natriuretic peptide levels are increased in heart failure (HF). Atrial (ANP) and
brain (BNP) natriuretic peptide mediate their effects preferentially through the natriuretic …
brain (BNP) natriuretic peptide mediate their effects preferentially through the natriuretic …
Compartmentation of natriuretic peptide signalling in cardiac myocytes: effects on cardiac contractility and hypertrophy
LR Moltzau, S Meier, KW Andressen… - Microdomains in the …, 2017 - Springer
Natriuretic peptides have received considerable attention in the recent years both as
biomarkers for heart failure and as treatment for the disease. Atrial (ANP) and B-type natriuretic …
biomarkers for heart failure and as treatment for the disease. Atrial (ANP) and B-type natriuretic …