RvD1 ameliorates LPS-induced acute lung injury via the suppression of neutrophil infiltration by reducing CXCL2 expression and release from resident alveolar …

…, AM Ali, QX Wu, Y Ye, HR Xu, SY Xiang… - International …, 2019 - Elsevier
Acute lung injury (ALI) and/or acute respiratory distress syndrome (ARDS) are life-threatening
critical syndromes characterized by the infiltration of a large number of inflammatory cells …

MCTR1 enhances the resolution of lipopolysaccharide‐induced lung injury through STAT6‐mediated resident M2 alveolar macrophage polarization in mice

…, HX Mei, Y Ye, HR Xu, SY Xiang… - Journal of cellular …, 2020 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is a fatal disease characterized by excessive
infiltration of inflammatory cells. MCTR1 is an endogenously pro‐resolution lipid mediator. We …

[HTML][HTML] RvD1 accelerates the resolution of inflammation by promoting apoptosis of the recruited macrophages via the ALX/FasL-FasR/caspase-3 signaling pathway

S Xiang, Y Ye, Q Yang, H Xu, C Shen, M Ma, S Jin… - Cell Death …, 2021 - nature.com
The uncontrolled inflammatory response caused by a disorder in inflammation resolution is
one of the reasons for acute respiratory distress syndrome (ARDS). The macrophage pool …

[HTML][HTML] Protectin conjugates in tissue regeneration 1 inhibits macrophage pyroptosis by restricting NLRP3 inflammasome assembly to mitigate sepsis via the cAMP …

…, HL Chen, HB Xu, DL Zhang, YA Zhang, SY Xiang… - Laboratory …, 2023 - Elsevier
Protectin conjugates in tissue regeneration 1 (PCTR1) is a novel anti-inflammatory and
proresolving lipid mediator biosynthesized from docosahexaenoic acid. Excessive activation of …

Resolvin conjugates in tissue regeneration 1 promote alveolar fluid clearance by activating alveolar epithelial sodium channels and Na, K-ATPase in …

Q Yang, H Xu, S Xiang, C Zhang, Y Ye, C Shen… - … of Pharmacology and …, 2021 - ASPET
Acute respiratory distress syndrome (ARDS), a common and fatal clinical condition, is
characterized by the destruction of epithelium and augmented permeability of the alveolar-…

LXA4 inhibits lipopolysaccharide-induced inflammatory cell accumulation by resident macrophages in mice

HX Mei, Y Ye, HR Xu, SY Xiang, Q Yang… - Journal of …, 2021 - Taylor & Francis
Introduction Alveolar macrophages that regulate the inflammatory response in lungs are the
main target cell for the treatment of inflammatory pulmonary pathologies, such as acute …

PDX regulates inflammatory cell infiltration via resident macrophage in LPS‐induced lung injury

…, HW Zhang, HX Mei, HR Xu, SY Xiang… - Journal of Cellular …, 2020 - Wiley Online Library
Inflammatory cell infiltration contributes to the pathogenesis of acute respiratory distress
syndrome (ARDS). Protectin DX (PDX), an endogenous lipid mediator, shows anti‐inflammatory …

Rosuvastatin enhances alveolar fluid clearance in lipopolysaccharide-induced acute lung injury by activating the expression of sodium channel and Na, K-ATPase via …

HR Xu, Q Yang, SY Xiang, PH Zhang, Y Ye… - Journal of …, 2021 - Taylor & Francis
Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are
devastating clinical conditions characterized by pulmonary epithelial damage and protein-rich …

RCTR1 promotes alveolar fluid clearance by activating alveolar epithelial sodium channels and Na, K-ATPase in LPS-induced acute lung injury

Q Yang, H Xu, S Xiang, C Zhang, Y Ye, C Shen… - … of Pharmacology and …, 2021 - ASPET
Acute respiratory distress syndrome (ARDS), a common and fatal clinical condition, is
characterized by the destruction of epithelium and augmented permeability of the alveolar-…

Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: II. The binding characterization with specific intramolecular G …

Q Yang, J Xiang, S Yang, Q Li, Q Zhou… - Nucleic acids …, 2010 - academic.oup.com
The supramolecular assembly of a novel cyanine dye, 3,3′-di(3-sulfopropyl)-4,5,4′,5′-dibenzo-9-ethyl-thiacarbocyanine
triethylammonium salt (ETC) was designed to verify specific …