User profiles for Shaoqing He

Shaoqing He

University of North Texas Health Science Center, North Texas Eye Research Center
Verified email at unthsc.edu
Cited by 1892

Targets of neuroprotection in glaucoma

S He, DL Stankowska, DZ Ellis… - Journal of Ocular …, 2018 - liebertpub.com
Progressive neurodegeneration of the optic nerve and the loss of retinal ganglion cells is a
hallmark of glaucoma, the leading cause of irreversible blindness worldwide, with primary …

[HTML][HTML] A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis

S He, C McPhaul, JZ Li, R Garuti, L Kinch… - Journal of Biological …, 2010 - ASBMB
Obesity and insulin resistance are associated with deposition of triglycerides in tissues other
than adipose tissue. Previously, we showed that a missense mutation (I148M) in PNPLA3 (…

A feed-forward loop amplifies nutritional regulation of PNPLA3

Y Huang, S He, JZ Li, YK Seo… - Proceedings of the …, 2010 - National Acad Sciences
The upsurge in prevalence of obesity has spawned an epidemic of nonalcoholic fatty liver
disease (NAFLD). Previously, we identified a sequence variant (I148M) in patatin-like …

[HTML][HTML] Endothelin B receptors contribute to retinal ganglion cell loss in a rat model of glaucoma

AZ Minton, NR Phatak, DL Stankowska, S He, HY Ma… - 2012 - journals.plos.org
Glaucoma is an optic neuropathy, commonly associated with elevated intraocular pressure (IOP)
characterized by optic nerve degeneration, cupping of the optic disc, and loss of retinal …

[HTML][HTML] Changes in ocular aquaporin-4 (AQP4) expression following retinal injury

A Dibas, MH Yang, S He, J Bobich, T Yorio - Molecular Vision, 2008 - ncbi.nlm.nih.gov
Purpose Changes in the expression of water channels or aquaporins (AQP) have been
reported in several diseases. However, such changes and mechanisms remain to be evaluated …

Effects of different loading strategies on the dynamic response and multi-physics fields distribution of PEMEC stack

X Zhang, B Wang, Y Xu, L Wu, F Zhang, S He, X Zhang… - Fuel, 2023 - Elsevier
Proton exchange membrane electrolysis cell (PEMEC) is a promising option for hydrogen
production with excellent dynamic response and the ability to operate at high current densities …

Numerical investigation on the feasibility of metal foam as flow field in alkaline anion exchange membrane fuel cell

…, Z Yang, Z Liu, C Tongsh, G Zhang, B Xie, S He… - Applied Energy, 2021 - Elsevier
Metal foam (MF) material is a promising alternative in fuel cell for its extremely porous
structure, high electrical conductivity, controllable permeability and strong mechanical strength. …

[HTML][HTML] Endothelin-1-mediated signaling in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in astrocytes

S He, G Prasanna, T Yorio - Investigative ophthalmology & visual …, 2007 - arvojournals.org
purpose. Endothelin (ET)-1 levels are increased in aqueous and vitreous humor in patients
with glaucoma and animal models of glaucoma. Whether the elevated ET-1 induces …

[HTML][HTML] Endothelin-1 mediated decrease in mitochondrial gene expression and bioenergetics contribute to neurodegeneration of retinal ganglion cells

RM Chaphalkar, DL Stankowska, S He, B Kodati… - Scientific Reports, 2020 - nature.com
Endothelin-1 (ET-1) is a vasoactive peptide that is elevated in aqueous humor as well as
circulation of primary open angle glaucoma (POAG) patients. ET-1 has been shown to promote …

[HTML][HTML] Upregulation of the endothelin A (ETA) receptor and its association with neurodegeneration in a rodent model of glaucoma

NR McGrady, AZ Minton, DL Stankowska, S He… - BMC neuroscience, 2017 - Springer
Background Primary open angle glaucoma is a heterogeneous group of optic neuropathies
that results in optic nerve degeneration and a loss of retinal ganglion cells (RGCs) ultimately …