Antidiabetic agents from medicinal plants

…, HC Lee, YH Kang, ES Kang, SK Kim - Current medicinal …, 2006 - ingentaconnect.com
Currently available therapeutic options for non-insulin-dependent diabetes mellitus, such as
dietary modification, oral hypoglycemics, and insulin, have limitations of their own. Many …

The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression

SK Kim, RF Novak - Pharmacology & therapeutics, 2007 - Elsevier
Endogenous factors, including hormones, growth factors and cytokines, play an important
role in the regulation of hepatic drug metabolizing enzyme expression in both physiological …

Attenuation of bacterial lipopolysaccharide-induced hepatotoxicity by betaine or taurine in rats

SK Kim, YC Kim - Food and Chemical Toxicology, 2002 - Elsevier
The effects of betaine or taurine on hepatotoxicity induced by lipopolysaccharide (LPS) were
examined in adult male SD rats. Rats were provided with drinking water containing either 1…

Effects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice

SK Kim, YC Kim - Journal of hepatology, 2005 - Elsevier
BACKGROUND/AIMS: We previously reported that acute betaine treatment induced significant
changes in the hepatic glutathione and cysteine levels in mice and rats. The present …

Alleviation of dimethylnitrosamine-induced liver injury and fibrosis by betaine supplementation in rats

SK Kim, JM Seo, YR Chae, YS Jung, JH Park… - Chemico-biological …, 2009 - Elsevier
Previous studies suggested that betaine intake might antagonize the induction of oxidative
stress-mediated acute liver injury through regulation of the sulfur–amino acid metabolism. In …

Insulin signaling regulates γ-glutamylcysteine ligase catalytic subunit expression in primary cultured rat hepatocytes

SK Kim, KJ Woodcroft, SS Khodadadeh… - Journal of Pharmacology …, 2004 - ASPET
Decreased glutathione (GSH) levels and γ-glutamylcysteine ligase (GCL) activity have been
observed in diabetic patients, and insulin reportedly increases GSH synthesis via increased …

Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice

SK Kim, KH Choi, YC Kim - Biochemical pharmacology, 2003 - Elsevier
Alterations of hepatic glutathione level by betaine were observed previously. In this study
effects of betaine administration (1000mg/kg, ip) on S-amino acid metabolism in rats and mice …

Effects of cysteine on amino acid concentrations and transsulfuration enzyme activities in rat liver with protein–calorie malnutrition

YG Kim, SK Kim, JW Kwon, OJ Park, SG Kim, YC Kim… - Life sciences, 2003 - Elsevier
The changes in amino acid concentrations and transsulfuration enzyme activities in liver
were investigated after 4-week fed on 23% casein diet (control group) and 5% casein diet …

Emotion recognition system using short-term monitoring of physiological signals

KH Kim, SW Bang, SR Kim - Medical and biological engineering and …, 2004 - Springer
A physiological signal-based emotion recognition system is reported. The system was
developed to operate as a user-independent system, based on physiological signal databases …

Development of a T1 Contrast Agent for Magnetic Resonance Imaging Using MnO Nanoparticles

…, ST Kim, SH Kim, SW Kim, KH Lim, KS Kim… - Angewandte …, 2007 - Wiley Online Library
Nanometer-sized colloidal particles (nanoparticles) have been extensively used in biomedical
applications as a result of their many useful electronic, optical, and magnetic properties …