User profiles for Salvatore Cuzzocrea
Salvatore CuzzocreaProfessore di Farmacologia Università di Messina Verified email at unime.it Cited by 64382 |
Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury
S Cuzzocrea, DP Riley, AP Caputi, D Salvemini - Pharmacological reviews, 2001 - ASPET
A vast amount of circumstantial evidence implicates oxygen-derived free radicals (especially
superoxide and hydroxyl radical) and high-energy oxidants (such as peroxynitrite) as …
superoxide and hydroxyl radical) and high-energy oxidants (such as peroxynitrite) as …
[HTML][HTML] Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update
R Siracusa, RD Paola, S Cuzzocrea… - International journal of …, 2021 - mdpi.com
Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …
A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats
Many human diseases are associated with the overproduction of oxygen free radicals that
inflict cell damage. A manganese(II) complex with a bis(cyclohexylpyridine)-substituted …
inflict cell damage. A manganese(II) complex with a bis(cyclohexylpyridine)-substituted …
[HTML][HTML] Effects of melatonin treatment in septic newborns
Free radicals have been implicated in the pathogenesis of neonatal sepsis and its complications.
This study was conducted to determine the changes in the clinical status and the serum …
This study was conducted to determine the changes in the clinical status and the serum …
A newly identified role for superoxide in inflammatory pain
ZQ Wang, F Porreca, S Cuzzocrea, K Galen… - … of Pharmacology and …, 2004 - ASPET
Novel classes of pain-relieving molecules are needed to fill the void between nonsteroidal
anti-inflammatory agents and narcotics. Our studies have identified superoxide as a novel …
anti-inflammatory agents and narcotics. Our studies have identified superoxide as a novel …
Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors
V Mollace, C Muscoli, E Masini, S Cuzzocrea… - Pharmacological …, 2005 - ASPET
The biosynthesis and release of nitric oxide (NO) and prostaglandins (PGs) share a number
of similarities. Two major forms of nitric-oxide synthase (NOS) and cyclooxygenase (COX) …
of similarities. Two major forms of nitric-oxide synthase (NOS) and cyclooxygenase (COX) …
[HTML][HTML] Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity
…, I Iavicoli, R Di Paola, A Koverech, S Cuzzocrea… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Modulation of endogenous cellular defense mechanisms represents an innovative
approach to therapeutic intervention in diseases causing chronic tissue damage, such as in …
approach to therapeutic intervention in diseases causing chronic tissue damage, such as in …
Antiinflammatory activity of melatonin in central nervous system
E Esposito, S Cuzzocrea - Current neuropharmacology, 2010 - ingentaconnect.com
Melatonin is mainly produced in the mammalian pineal gland during the dark phase. Its
secretion from the pineal gland has been classically associated with circadian and circanual …
secretion from the pineal gland has been classically associated with circadian and circanual …
Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin
F Fulia, E Gitto, S Cuzzocrea, RJ Reiter… - Journal of pineal …, 2001 - Wiley Online Library
Free radicals have been implicated in the pathogenesis of neonatal asphyxia and its
complications. This study measured a product of lipid peroxidation, malondialdehyde, and the nitrite…
complications. This study measured a product of lipid peroxidation, malondialdehyde, and the nitrite…
Ligands of the peroxisome proliferator‐activated receptors (PPAR‐γ and PPAR‐α) reduce myocardial infarct size
…, H MOTA‐FILIPE, S Cuzzocrea… - The FASEB …, 2002 - Wiley Online Library
This study was designed to investigate the effects of various chemically distinct activators of
PPAR‐γ and PPAR‐α in a rat model of acute myocardial infarction. Using Northern blot …
PPAR‐γ and PPAR‐α in a rat model of acute myocardial infarction. Using Northern blot …