User profiles for S F Lee

Steven F. Lee

Professor of Biophysical Chemistry, University of Cambridge
Verified email at cam.ac.uk
Cited by 4933

Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements

…, D Munera, KS Robinson, SF Lee… - Molecular …, 2011 - Wiley Online Library
… those encoded within LEE and a number of non-LEE effectors, are shared by all A/E
pathogens (Iguchi et al., 2009). However, the repertoire of the remaining non-LEE effectors varies …

Gold and iron oxide hybrid nanocomposite materials

…, S Xuan, X Zhu, D Wang, CP Chak, SF Lee… - Chemical Society …, 2012 - pubs.rsc.org
This critical review provides an overview of current research activities that focused on the
synthesis and application of multi-functional gold and iron oxide (Au–FexOy) hybrid …

Brightening, blinking, bluing and bleaching in the life of a quantum dot: friend or foe?

SF Lee, MA Osborne - ChemPhysChem, 2009 - Wiley Online Library
Lee et al.106 have recently shown a significant enhancement as well as decay in the …
Steven Lee completed his D.Phil. in physical chemistry (Thesis: Photodynamics for Single …

[HTML][HTML] Urinary sodium and potassium excretion, mortality, and cardiovascular events

…, X Wang, L Liu, H Yan, SF Lee… - … England Journal of …, 2014 - Mass Medical Soc
Background The optimal range of sodium intake for cardiovascular health is controversial.
Methods We obtained morning fasting urine samples from 101,945 persons in 17 countries …

Perpendicular giant magnetoresistances of Ag/Co multilayers

WP Pratt Jr, SF Lee, JM Slaughter, R Loloee… - Physical review …, 1991 - APS
We present measurements at 4.2 K of the magnetoresistance (MR) measured with the current
perpendicular to the layer planes (CPP) of equal and unequal thickness Ag/Co magnetic …

3D structures of individual mammalian genomes studied by single-cell Hi-C

…, D Lando, S Basu, LP Atkinson, Y Cao, SF Lee… - Nature, 2017 - nature.com
The folding of genomic DNA from the beads-on-a-string-like structure of nucleosomes into
higher-order assemblies is crucially linked to nuclear processes. Here we calculate 3D …

[HTML][HTML] Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

H Tu, O Nelson, A Bezprozvanny, Z Wang, SF Lee… - Cell, 2006 - cell.com
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder.
Mutations in presenilins 1 and 2 (PS1 and PS2) account for ∼40% of familial AD (FAD) cases. …

[HTML][HTML] Nicastrin functions as a γ-secretase-substrate receptor

S Shah, SF Lee, K Tabuchi, YH Hao, C Yu, Q LaPlant… - Cell, 2005 - cell.com
γ-secretase catalyzes the intramembrane cleavage of amyloid precursor protein (APP) and
Notch after their extracellular domains are shed by site-specific proteolysis. Nicastrin is an …

Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry

M Joron, L Frezal, RT Jones, NL Chamberlain, SF Lee… - Nature, 2011 - nature.com
Supergenes are tight clusters of loci that facilitate the co-segregation of adaptive variation,
providing integrated control of complex adaptive phenotypes 1 . Polymorphic supergenes, in …

Universal primers for fluorescent labelling of PCR fragments—an efficient and cost‐effective approach to genotyping by fluorescence

MJ Blacket, C Robin, RT Good, SF Lee… - Molecular ecology …, 2012 - Wiley Online Library
Directly labelling locus‐specific primers for microsatellite analysis is expensive and a
common limitation to small‐budget molecular ecology projects. More cost‐effective end‐labelling …